Isabella Tarissi de Jacobis

TL;DR: These practical guidelines related to Kawasaki disease are aimed at improving the rate of treatment with intravenous immunoglobulin and the overall potential development of coronary artery abnormalities in KD.

TL;DR: An imbalance between the production and the detoxification of reactive oxygen species and reactive nitrogen species (ROS/RNS) can be implicated in many pathological processes, and platelets are best known as primary mediators of hemostasis.

TL;DR: This second part of practical Guidelines related to Kawasaki disease has the goal of contributing to prompt diagnosis and most appropriate treatment of KD resistant forms and cardiovascular complications, including non-pharmacologic treatments, follow-up, lifestyle and prevention of cardiovascular risks in the long-term through a set of 17 recommendations.

TL;DR: It is hypothesized that the simultaneous oxidative and nitrative stress occurrence in the blood of KD patients may play a pathogenetic role in the cardiovascular complications often associated with this rare disease.

TL;DR: The state of the art of pathogenetic mechanisms of Kawasaki disease are summarized, underscoring the relevance of haematological features as a novel field of investigation.