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Isabelle Tillie-Leblond

Researcher at university of lille

Publications -  122
Citations -  5987

Isabelle Tillie-Leblond is an academic researcher from university of lille. The author has contributed to research in topics: Asthma & Inflammation. The author has an hindex of 38, co-authored 122 publications receiving 5611 citations. Previous affiliations of Isabelle Tillie-Leblond include French Institute of Health and Medical Research & Lille University of Science and Technology.

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Combined pulmonary fibrosis and emphysema: a distinct underrecognised entity

TL;DR: The authors individualise the computer tomography-defined syndrome of combined pulmonary fibrosis and emphysema characterised by subnormal spirometry, severe impairment of gas exchange, high prevalence of pulmonary hypertension, and poor survival.
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Bronchial Neutrophilia in Patients with Noninfectious Status Asthmaticus

TL;DR: Investigation of the contribution of different cell types and cellular mediators to the pathogenesis of status asthmaticus indicates that bronchial inflammation in SA differs from bronchia inflammation in mild asthma, and persistentBronchial neutrophilia is associated with increased eosinophils and mast cells in the early phase of SA.
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Clinical COPD phenotypes: a novel approach using principal component and cluster analyses

TL;DR: Importantly, subjects with comparable airflow limitation (FEV1) belonged to different phenotypes and had marked differences in age, symptoms, comorbidities and predicted mortality, underscore the need for novel multidimensional COPD classification for improving patient care and quality of clinical trials.
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Pulmonary Embolism in Patients with Unexplained Exacerbation of Chronic Obstructive Pulmonary Disease: Prevalence and Risk Factors

TL;DR: This study prospectively evaluated PE in patients with COPD exacerbation of unknown origin and examined factors associated with the presence of PE, including the Geneva score, in a single-center study.
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Balance between Proinflammatory Cytokines and Their Inhibitors in Bronchial Lavage from Patients with Status Asthmaticus

TL;DR: Despite a marked increase of anti-inflammatory mediators in BL from patients with SA, the net inflammatory activity was found to be proinflammatory and mainly due to the presence of bioactive IL-1beta and to a lesser extent TNF-alpha.