Isis Akemi Katayama

TL;DR: Compared to control animals, IL-4 content was elevated in the fetal portion of the placenta in rats exposed to air pollution before and during pregnancy, suggesting that a placental inflammatory reaction may have occurred in response to exposure to fine particulate matter.

TL;DR: In this article, male Wistar rats were fed a normal (NSD: 1.3% NaCl), high 4 (HSD4: 4%), or high 8(HSD8: 8%) salt diet from weaning until 18 wk of age.

TL;DR: Evidence from the present study suggests that salt-induced AT(1) receptor internalization is probably due to angiotensin II binding, and hydralazine prevented high blood pressure (BP) and fibrosis, but not cardiomyocyte hypertrophy.

TL;DR: The primary finding was the occurrence of significant BP-independent CH in the HS+HZ group and a partial or total prevention of such hypertrophy via treatment with NAC or LOS, and the link of oxidative stress with CH in the authors' experimental model is very interesting and stimulates further evaluation for its full comprehension.

TL;DR: Lowering ERAP1 led to volume expansion and increased BP in males and females, whereas in females the volume expansion was due to impaired renovascular function with normal ALDO levels.