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Ivanka Tsakovska
Researcher at Bulgarian Academy of Sciences
Publications - 63
Citations - 1167
Ivanka Tsakovska is an academic researcher from Bulgarian Academy of Sciences. The author has contributed to research in topics: Chemistry & Medicine. The author has an hindex of 16, co-authored 52 publications receiving 906 citations.
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Book ChapterDOI
In silico models for acute systemic toxicity
TL;DR: An overview of the regulatory requirements for acute systemic toxicity information in the European Union is given, and the availability of structure-based computational models that are available and potentially useful in the assessment of acute systemicoxicity are reviewed.
Journal ArticleDOI
ADME/Tox Properties and Biochemical Interactions of Silybin Congeners: In silico Study.
Antonia Diukendjieva,Merilin Al Sharif,Petko Alov,Tania Pencheva,Ivanka Tsakovska,Ilza Pajeva +5 more
TL;DR: This study explored important ADME/Tox properties and biochemical interactions of selected flavonolignans using in silico methods and predicted toxic effects and metabolic transformations using knowledge-based expert systems Derek Nexus and Meteor Nexus.
Journal Article
The Use of Computational Methods for the Assessment of Chemicals in REACH
Ivanka Tsakovska,Andrew Worth +1 more
TL;DR: In this paper, an overview of the use of computational methods in chemicals hazard and risk assessment under the Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH) legislation is provided.
Journal ArticleDOI
Natural Chain-Breaking Antioxidants and Their Synthetic Analogs as Modulators of Oxidative Stress.
Vessela D. Kancheva,Maria Antonietta Dettori,Davide Fabbri,Petko Alov,Silvia Angelova,Adriana Slavova-Kazakova,Paola Carta,Valerii A Menshov,O. I. Yablonskaya,Aleksei V. Trofimov,Aleksei V. Trofimov,Ivanka Tsakovska,Luciano Saso +12 more
TL;DR: In this paper, 40 phenolic antioxidants were selected for a comparative study and analysis of their chain-breaking antioxidant activity, and thus as modulators of oxidative stress, including natural and natural-like ortho-methoxy and orthohydroxy phenols.
Journal ArticleDOI
Development of new COSMOS oRepeatDose and non-cancer Threshold of Toxicological Concern (TTC) databases to support alternative testing methods for cosmetics related chemicals
Chihae Yang,Massimo Ambrosio,Kirk Arvidson,Sue Barlow,Alan R. Boobis,Maria Checheva,Mark T. D. Cronin,Susan P. Felter,Elena Fioravanzo,Heli M. Hollnagel,Dimitar Hristozov,Kristi L. Muldoon Jacobs,Detlef Keller,Aleksandra Mostrag-Szylchtying,Mark D. Nelms,James F. Rathman,Andrea Richarz,Ivanka Tsakovska,Stephane Vidry,Vessela Vitcheva,Andrew Worth +20 more