J
J. Donald Capra
Researcher at Oklahoma Medical Research Foundation
Publications - 1
Citations - 1015
J. Donald Capra is an academic researcher from Oklahoma Medical Research Foundation. The author has contributed to research in topics: Antibody & Original antigenic sin. The author has an hindex of 1, co-authored 1 publications receiving 939 citations. Previous affiliations of J. Donald Capra include University of Oklahoma Health Sciences Center.
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Rapid cloning of high-affinity human monoclonal antibodies against influenza virus
Jens Wrammert,Kenneth J. Smith,Joseph I. Miller,William A. Langley,Kenneth E. Kokko,Christian P. Larsen,Nai-Ying Zheng,Israel Mays,Lori Garman,Christina Helms,Judith A. James,Judith A. James,Gillian M. Air,J. Donald Capra,J. Donald Capra,Rafi Ahmed,Patrick C. Wilson,Patrick C. Wilson +17 more
TL;DR: The panel of influenza-virus-specific human mAbs allowed us to address the issue of original antigenic sin (OAS): the phenomenon where the induced antibody shows higher affinity to a previously encountered influenza virus strain compared with the virus strain present in the vaccine.