J
J. H. Lagendijk
Publications - 6
Citations - 434
J. H. Lagendijk is an academic researcher. The author has contributed to research in topics: Keratin 20 & Adenocarcinoma. The author has an hindex of 4, co-authored 5 publications receiving 422 citations.
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Tracing the origin of adenocarcinomas with unknown primary using immunohistochemistry: differential diagnosis between colonic and ovarian carcinomas as primary sites.
TL;DR: Most ovarian carcinomas, including the mucinous ones, can be discriminated with high probability from colonic carcinomas using a panel of three antibodies directed against CEA, cytokeratin 7, and vimentin, which appeared to be CK7 and CEA.
Journal ArticleDOI
Immunohistochemical differentiation between primary adenocarcinomas of the ovary and ovarian metastases of colonic and breast origin. Comparison between a statistical and an intuitive approach.
TL;DR: Using a semiquantitative assessment of the immunostaining results by a restricted panel of six antibodies with stepwise discriminant analysis, 80-90% of the adenocarcinomas of colon, breast, and ovary can be correctly classified.
Journal ArticleDOI
Value of a panel of antibodies to identify the primary origin of adenocarcinomas presenting as bladder carcinoma
R. Torenbeek,J. H. Lagendijk,P. J. Van Diest,H. Bril,F. J. J. M. Van De Molengraft,C. J. L. M. Meijer +5 more
TL;DR: For the surgical pathologist, a panel of antibodies consisting of CEA, PSA, OC125 and vimentin is helpful to differentiate primary urinary bladder adenocarcinomas from adenOCarcinoma originating from prostate and endometrium, less helpful in differentiation with urachal carcinoma, and not helpful with colonic, cervical and ovarian carcinoma.
Journal ArticleDOI
Progressive Deregulation of the Cell Cycle With Higher Tumor Grade in the Stroma of Breast Phyllodes Tumors
TL;DR: The stromal component of mammary phyllodes tumors displays an increasing level of cell cycle deregulation with higher tumor grade and the epithelial compartment mostly remains inconspicuous; several combinations of aberrantly expressed cell cycle proteins seem important in theStromal progression of phyllode tumors.
differentiation between primary adenocarcinomas oftheovary and ovarian metastasesofcolonic andbreast origin. Comparison between a statistical andan intuitive approach
TL;DR: Aim-Todiscriminate betweenadenocarcinomas that are primarytotheovary and metastatic to theovary, especially of colonic and breast origin, by stepwise discriminant analysis orcision tree, using immunohistochemistry.