J
J. Inglese
Researcher at University of Hohenheim
Publications - 2
Citations - 148
J. Inglese is an academic researcher from University of Hohenheim. The author has contributed to research in topics: Fusion protein & Heterotrimeric G protein. The author has an hindex of 2, co-authored 2 publications receiving 145 citations.
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Olfactory desensitization requires membrane targeting of receptor kinase mediated by beta gamma-subunits of heterotrimeric G proteins.
TL;DR: It is demonstrated that odorants stimulate translocation of GRK3 from cytosol to membranes in isolated rat olfactory cilia, suggesting that beta gamma-subunits may physiologically regulate a G protein-coupled receptor kinase and that enzyme translocation may be a general and required feature of the activity of some members of this enzyme family.