J
J.L. Sarthou
Researcher at Pasteur Institute
Publications - 6
Citations - 150
J.L. Sarthou is an academic researcher from Pasteur Institute. The author has contributed to research in topics: Virus & Yellow fever. The author has an hindex of 6, co-authored 6 publications receiving 146 citations.
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Characterization of an antigen-antibody system associated with epidemic non-A,non-B hepatitis in west africa and experimental transmission of an infectious agent to primates
TL;DR: Using the immunoenzymatic test employing monkey IgM on solid phase and enzyme-labelled IgG purified from sera of patients convalescing from NANBH, the antigen associated with the possible causative NANbH agent is identified and confirmed the existence of a distinct human N ANBH agent.
Journal Article
[Yellow fever virus, dengue 2 and other arboviruses isolated from mosquitos, in Burkina Faso, from 1983 to 1986. Entomological and epidemiological considerations]
Vincent Robert,M. Lhuillier,D. Meunier,J.L. Sarthou,N. Monteny,J.P. Digoutte,M. Cornet,M. Germain,Roger Cordellier +8 more
TL;DR: The observations confirm that the southern portion of the Sudan savanna zone of West Africa is the setting of a customary circulation of yellow fever virus and therefore belongs to the endemic emergence zone and two distinct cycles for dengue 2 virus, one urban and one selvatic, which could coexist simultaneously in the same region.
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Intérêt des IgM antiamariles dans le diagnostic et la surveillance épidémiologique de la fièvre jaune
M. Lhuillier,J.L. Sarthou +1 more
TL;DR: Evidence of IgM in a single serum after viraemia allows a good presumptive diagnostic, thus facilitating epidemiological investigations particularly in the detection of the first cases, and the advantages of the rapid detection of anti-yellow fever IgM have been shown in the Detection of several sporadic cases.
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Immunological characterization of a viral agent involved in epidemic and sporadic non-A,non-B hepatitis
Jacques Pillot,Jacques Pillot,M.D. Sharma,M.D. Sharma,Yamina Lazizi,Yamina Lazizi,Agata Budkowska,Agata Budkowska,Charles Dauguet,M. Galimand,J.L. Sarthou +10 more
TL;DR: An antigen associated with non-A,non-B (NANB) virus was characterized in patients suffering from epidemic and sporadic cases of NANB hepatitis, and antibodies were detected in sera from African patients with epidemic or endemic NANb hepatitis, as well as from European patients with endemic N ANB hepatitis.
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Intérêt du titrage par ELISA des IgM spécifiques pour le diagnostic et la surveillance de la circulation selvatique des flavivirus en Afrique
TL;DR: The combined use of end-point IgM ELISA and virus isolation permitted a specific diagnosis in all cases of yellow fever studied during the epidemic in Burkina Faso, and provided a means of rapid diagnosis using a single serum sample, and should be applied in programs of surveillance and epidemic investigation.