J
J.M. Wharton
Researcher at Duke University
Publications - 16
Citations - 784
J.M. Wharton is an academic researcher from Duke University. The author has contributed to research in topics: Defibrillation & Defibrillation threshold. The author has an hindex of 6, co-authored 16 publications receiving 776 citations.
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Journal ArticleDOI
Stimulus-induced critical point. Mechanism for electrical initiation of reentry in normal canine myocardium.
D. W. Frazier,Patrick D. Wolf,J.M. Wharton,Anthony S.L. Tang,William M. Smith,Raymond E. Ideker +5 more
TL;DR: The hypothesis was tested that the field of a premature (S2) stimulus, interacting with relatively refractory tissue, can create unidirectional block and reentry in the absence of nonuniform dispersion of recovery when S2 field strengths and tissue refractoriness are uniformally dispersed at an angle to each other.
Journal ArticleDOI
Cardiac potential and potential gradient fields generated by single, combined, and sequential shocks during ventricular defibrillation.
J.M. Wharton,Patrick D. Wolf,Warren Smith,Peng Sheng Chen,D. W. Frazier,S Yabe,N. D. Danieley,Raymond E. Ideker +7 more
TL;DR: Defibrillation fields created by small epicardial electrodes are very uneven and achievement of a certain minimum potential gradient over both ventricles is necessary for ventricular defibrillation; the difference in shock strengths required to achieve this minimum gradient overBoth ventricle may explain the differences in DIFTs for various electrode configurations.
Journal ArticleDOI
Electrophysiological Effects of Monophasic and Biphasic Stimuli in Normal and Infarcted Dogs
J.M. Wharton,Vincent Richard,Charles E. Murry,E. G. Dixon,Keith A. Reimer,J T Meador,Warren Smith,Raymond E. Ideker +7 more
TL;DR: The increased defibrillation efficacy of the biphasic waveform is independent of its ability to activate fully repolarized myocardium and cannot be explained by a greater ability of biphasics waveforms to activate partially depolarized tissue.
Journal ArticleDOI
Internal Atrial Defibrillation in Humans Improved Efficacy of Biphasic Waveforms and the Importance of Phase Duration
TL;DR: For IAD in humans, biphasicWaveforms were more efficacious than monophasic waveforms and this improved efficacy is related to the total duration and each individual phase duration of the biphaic waveform.
Journal ArticleDOI
Effect of Ebstein's anomaly on short- and long-term outcome of surgically treated patients with Wolff-Parkinson-White syndrome.
Joyce C. Pressley,J.M. Wharton,Anthony S.L. Tang,James E. Lowe,John J. Gallagher,Eric N. Prystowsky +5 more
TL;DR: Patients with Ebstein's anomaly are improved significantly after accessory pathways ablation, and the presence of this anomaly should not preclude accessory pathway ablation in these patients.