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Jacek Z. Kubiak

Researcher at Centre national de la recherche scientifique

Publications -  175
Citations -  4776

Jacek Z. Kubiak is an academic researcher from Centre national de la recherche scientifique. The author has contributed to research in topics: Xenopus & Cyclin-dependent kinase 1. The author has an hindex of 32, co-authored 156 publications receiving 4259 citations. Previous affiliations of Jacek Z. Kubiak include University of Rennes & University of Paris.

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Microtubule and chromatin behavior follow MAP kinase activity but not MPF activity during meiosis in mouse oocytes

TL;DR: The precise timing of MAP kinase activation versus MPF activation is studied during mouse oocyte maturation and, in parallel, morphological events such as changes in microtubule organization and chromatin condensation are studied.
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Mos is required for MAP kinase activation and is involved in microtubule organization during meiotic maturation in the mouse.

TL;DR: Observations present the first evidence, in intact oocytes, of a role for the Mos/.../MAP kinase cascade in the control of microtubule and chromatin organization during meiosis.
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The metaphase II arrest in mouse oocytes is controlled through microtubule-dependent destruction of cyclin B in the presence of CSF.

TL;DR: It is reported that in mouse oocytes a CSF‐like activity is involved in the M II arrest and that the high activity of MPF is maintained through a continuous equilibrium between cyclin B synthesis and degradation, which is also dependent upon the three‐dimensional organization of the spindle.
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Mouse oocytes gradually develop the capacity for activation during the metaphase II arrest

TL;DR: Depending on the type of activating stimulus, oocytes exhibit the capacity for full activation at different ages, and the oocyte arrest in M III is similar to M II and can be released by subsequent activation.
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Kinetochore Fibers Are Not Involved in the Formation of the First Meiotic Spindle in Mouse Oocytes, but Control the Exit from the First Meiotic M Phase

TL;DR: The spindle assembly pathway and its role in the progression of the first meiotic M phase in mouse oocytes is investigated and the ability of kinetochores to interact with microtubules is acquired at the end of thefirst meioticM phase and determines the timing of polar body extrusion.