Some Typical Advances in the Synthetic Applications of Allenes

Allenes are the simplest class of cumulenes, with two contiguous CC bonds, and show unique physical and chemical properties. These features make allenes particularly attractive in modern organic chemistry. In this Review, attention is paid to the advances made in catalytic asymmetric synthesis and natural product syntheses based on well-established reactions of allenes, such as propargylation, addition, cycloaddition, cycloisomerization, cyclization, etc., with or without catalysts. Their versatile reactivity, substituent-loading ability, axial to center chirality transfer, and controllable selectivity allow access to target molecules by unique and efficient approaches. The main topics in this Review are presented with selected examples from 2003 to 2011.

Allenes in Catalytic Asymmetric Synthesis and Natural Product Syntheses

Dioxiranes: a new class of powerful oxidants

Radical reactions in organic synthesis

the “973” Project from the MOST of China (2012CB725302);the National Natural Science Foundation of China (21025206;20832003;20972118)

Aerobic Oxysulfonylation of Alkenes Leading to Secondary and Tertiary β‐Hydroxysulfones

Alkylation a l'aide d'halogenures d'alkyle en presence d'halogenures de tetrabutylammonium dans un melange eau-benzene et acetone

Synthesis of sulfones by phase-transfer alkylation of arenesulfinate salts

Preparation d'halogenures allenyliques de structure (CH 3 ) 2 C=C=CH(CH 2 ) n X avec n=3 a 6 et etude de leurs reactions avec (n-C 4 H 9 ) 3 SnH pour donner les radicaux correspondants dont on examine les cyclisateurs. Influence de la longueur de la chaine sur la facilite de la cyclisation

Jack K. Crandall

Papers

Synthesis of sulfones by phase-transfer alkylation of arenesulfinate salts

Cyclizations of .omega.-allenyl radicals

Allene epoxidation. Efficient synthesis and synthetic conversions of 1,4-dioxaspiro[2.2]pentanes

The formation of orthoquinones in the dimethyldioxirane oxidation of phenols

Siloxanes from the hydrolysis of isopropyltrimethoxysilane