J
Jacques L. Mizrahi
Researcher at Eli Lilly and Company
Publications - 2
Citations - 494
Jacques L. Mizrahi is an academic researcher from Eli Lilly and Company. The author has contributed to research in topics: PRKCE & Caspase 3. The author has an hindex of 2, co-authored 2 publications receiving 489 citations.
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Journal ArticleDOI
Increased Protein Kinase C Activity and Expression of Ca2+-Sensitive Isoforms in the Failing Human Heart
Nancy Bowling,Richard A. Walsh,Guojie Song,Thomas B. Estridge,George E. Sandusky,Rebecca L. Fouts,Karen Mintze,Todd Pickard,Robert L. Roden,Michael R. Bristow,Hani N. Sabbah,Jacques L. Mizrahi,Gianni Gromo,George L. King,Chris J. Vlahos +14 more
TL;DR: In failed human heart, PKC-beta1 and -beta2 expression and contribution to total PKC activity are significantly increased, which may signal a role for Ca2+-sensitive PKC isoforms in cardiac mechanisms involved in heart failure.
Journal ArticleDOI
Involvement of caspase 3- and 8-like proteases in ceramide-induced apoptosis of cardiomyocytes.
TL;DR: Data suggest that caspases 3- and 8-related proteases are involved in ceramide-induced cardiomyocyte apoptosis.