J
Jae Young Lee
Researcher at National Institutes of Health
Publications - 1
Citations - 338
Jae Young Lee is an academic researcher from National Institutes of Health. The author has contributed to research in topics: DNA repair & ATP hydrolysis. The author has an hindex of 1, co-authored 1 publications receiving 314 citations.
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UvrD Helicase Unwinds DNA One Base Pair at a Time by a Two-Part Power Stroke
Jae Young Lee,Wei Yang +1 more
TL;DR: A series of crystal structures of the UvrD helicase complexed with DNA and ATP hydrolysis intermediates reveal that ATP binding alone leads to unwinding of 1 base pair by directional rotation and translation of the DNA duplex, and ADP and Pi release leads to translocation of the developing single strand.