J
Jafar Majidi
Researcher at Tabriz University of Medical Sciences
Publications - 101
Citations - 1731
Jafar Majidi is an academic researcher from Tabriz University of Medical Sciences. The author has contributed to research in topics: Antibody & Monoclonal antibody. The author has an hindex of 21, co-authored 99 publications receiving 1405 citations.
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Phage display as a promising approach for vaccine development.
Leili Aghebati-Maleki,Babak Bakhshinejad,Behzad Baradaran,Morteza Motallebnezhad,Ali Aghebati-Maleki,Hamid Nickho,Mehdi Yousefi,Jafar Majidi +7 more
TL;DR: The ability to produce combinatorial peptide libraries with a highly diverse pool of randomized ligands has transformed phage display into a straightforward, versatile and high throughput screening methodology for the identification of potential vaccine candidates against different diseases in particular microbial infections.
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Toll-Like Receptors in the Pathogenesis of Autoimmune Diseases.
TL;DR: It is demonstrated how TLRs pathways could be involved in autoimmune disorders and their therapeutic application with data rising predominantly from human patients and animal models of autoimmune disease.
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Developmental minocycline treatment reverses the effects of neonatal immune activation on anxiety- and depression-like behaviors, hippocampal inflammation, and HPA axis activity in adult mice.
TL;DR: Results indicated that neonatal immune activation resulted in increased anxiety and depression-like symptoms, HPA-axis-hyperactivity, and elevated the levels of TNF-α and IL-1β in the hippocampus in response to stress in adulthood, and Interestingly, developmental minocycline treatment significantly reduced the abnormalities induced by neonatal inflammation in adult mice.
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Target therapy of cancer: implementation of monoclonal antibodies and nanobodies.
TL;DR: The emergence of recombinant technologies, transgenic animals and phage display technology has revolutionized the selection, humanization and production of antibodies.
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The use of nanoparticles as a promising therapeutic approach in cancer immunotherapy
TL;DR: The current review sheds some light on the place of nanotechnology in cancer drug delivery, and introduces nanomaterials and their specific characteristics that can be used in tumor therapy.