J
Jaime Aguilera
Researcher at Spanish National Research Council
Publications - 10
Citations - 574
Jaime Aguilera is an academic researcher from Spanish National Research Council. The author has contributed to research in topics: Saccharomyces cerevisiae & Methylglyoxal. The author has an hindex of 8, co-authored 10 publications receiving 540 citations.
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Cold response in Saccharomyces cerevisiae: new functions for old mechanisms
TL;DR: There is now enough experimental evidence to conclude that exposure to low temperature protects yeast cells against freeze injury through the cold-induced accumulation of trehalose, glycerol and heat-shock proteins.
Cold response in Saccharomyces cerevisiae: New functions for old mechanisms. FEMS Microbiol Rev
TL;DR: In this paper, the physiological significance of cold-shock responses in yeast has been discussed, emphasizing the molecular mechanisms that generate and transmit cold signals and alternative cold-stress generators and transducers.
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The Saccharomyces cerevisiae aldose reductase is implied in the metabolism of methylglyoxal in response to stress conditions.
TL;DR: In vitro and in vivo assays of yeast aldose reductase activity indicate that the metabolism of methylglyoxal is stimulated under stress conditions; and they support a methyl Glyoxal degradative pathway, in which this compound is metabolised by the action of aldOSE reduct enzyme.
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The HOG MAP kinase pathway is required for the induction of methylglyoxal-responsive genes and determines methylglyoxal resistance in Saccharomyces cerevisiae
TL;DR: The results suggest that the basal activity of the HOG‐pathway serves to amplify the expression of MG‐responsive genes under non‐inducing and inducing conditions, ensuring cell protection against this toxic glycolytic by‐product.
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Yeast cells display a regulatory mechanism in response to methylglyoxal
TL;DR: In Saccharomyces cerevisiae, MG exposure increased the internal MG content and activated the expression of GLO1 and GRE3, two genes involved in MG detoxification; GPD1, the gene for glycerol synthesis; and T PS1 and TPS2, the trehalose pathway genes, which appeared to indicate that up-variations in the intracellular content of the toxic compound are perceived by the cell as a primary signal to trigger the transcriptional response.