J
Jaime Steinsapir
Researcher at Harvard University
Publications - 1
Citations - 110
Jaime Steinsapir is an academic researcher from Harvard University. The author has contributed to research in topics: Selenocysteine & Iodothyronine deiodinase. The author has an hindex of 1, co-authored 1 publications receiving 107 citations.
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Substrate-induced down-regulation of human type 2 deiodinase (hD2) is mediated through proteasomal degradation and requires interaction with the enzyme's active center.
TL;DR: Sub substrate-induced loss of D2 activity is due to proteasomal degradation of the enzyme and requires interaction with the catalytic center of the protein.