J
Jake A Ruddy
Researcher at Johns Hopkins University School of Medicine
Publications - 13
Citations - 582
Jake A Ruddy is an academic researcher from Johns Hopkins University School of Medicine. The author has contributed to research in topics: Vaccination & Medicine. The author has an hindex of 6, co-authored 13 publications receiving 196 citations. Previous affiliations of Jake A Ruddy include Johns Hopkins University.
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Journal ArticleDOI
High antibody response to two-dose SARS-CoV-2 messenger RNA vaccination in patients with rheumatic and musculoskeletal diseases.
Jake A Ruddy,Caoilfhionn M Connolly,Brian J. Boyarsky,William A. Werbel,Lisa Christopher-Stine,Jacqueline Garonzik-Wang,Dorry L. Segev,Julie J. Paik +7 more
TL;DR: In this paper, the SARS-CoV-2 mRNA vaccination elicited high immunogenicity in immunocompetent people in the original vaccine trials,1 2 though recent studies have shown blunted immunogenity in patients with rheumatic and musculoskeletal diseases (RMDs) after a single dose and case reports of non-response after two doses.
Journal ArticleDOI
Antibody response to a single dose of SARS-CoV-2 mRNA vaccine in patients with rheumatic and musculoskeletal diseases.
Brian J. Boyarsky,Jake A Ruddy,Caoilfhionn M Connolly,Michael T Ou,William A. Werbel,Jacqueline Garonzik-Wang,Dorry L. Segev,Julie J. Paik +7 more
TL;DR: The immune response to SARS-CoV-2 messenger RNA (mRNA) vaccines in patients with rheumatic and musculoskeletal diseases (RMD) is undefined because these individuals were largely excluded from phase I-III studies.
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Safety and Reactogenicity of 2 Doses of SARS-CoV-2 Vaccination in Solid Organ Transplant Recipients.
Michael T. Ou,Brian J. Boyarsky,Jennifer D. Motter,Ross S. Greenberg,Aura T. Teles,Jake A Ruddy,Michelle R Krach,Vedant S Jain,William A. Werbel,Robin K. Avery,Allan B. Massie,Dorry L. Segev,Dorry L. Segev,Jacqueline Garonzik-Wang +13 more
TL;DR: In this paper, the safety and reactogenicity of SARS-CoV-2 mRNA vaccines in transplant recipients were studied using a modified Poisson regression model, and the associations between characteristics and reactions were evaluated using modified poisson regression.
Journal ArticleDOI
Disease Flare and Reactogenicity in Patients with Rheumatic and Musculoskeletal Diseases Following Two-Dose SARS-CoV-2 Messenger RNA Vaccination.
Caoilfhionn M Connolly,Jake A Ruddy,Brian J. Boyarsky,Iulia Barbur,William A. Werbel,Duvuru Geetha,Jacqueline Garonzik-Wang,Dorry L. Segev,Dorry L. Segev,Lisa Christopher-Stine,Julie J. Paik +10 more
TL;DR: In this paper, the authors evaluated disease flare and post vaccination reactions (reactogenicity) in patients with rheumatic and musculoskeletal diseases (RMDs) following 2-dose SARS-CoV-2 messenger RNA (mRNA) vaccination.
Journal ArticleDOI
Safety and antibody response to two-dose SARS-CoV-2 messenger RNA vaccination in persons with HIV.
Jake A Ruddy,Brian J. Boyarsky,Justin R. Bailey,Andrew H. Karaba,Jacqueline Garonzik-Wang,Dorry L. Segev,Christine M. Durand,William A. Werbel +7 more
TL;DR: In this article, a study of SARS-CoV-2 mRNA vaccination in 14 persons with HIV demonstrated uniformly high anti-SARS receptor binding domain antibody titers after two doses.