J
James A. Carson
Researcher at University of Tennessee Health Science Center
Publications - 168
Citations - 8777
James A. Carson is an academic researcher from University of Tennessee Health Science Center. The author has contributed to research in topics: Skeletal muscle & Cachexia. The author has an hindex of 49, co-authored 157 publications receiving 7554 citations. Previous affiliations of James A. Carson include University of South Carolina & Shriners Hospitals for Children - Galveston.
Papers
More filters
Journal ArticleDOI
Carbohydrate ingestion influences skeletal muscle cytokine mRNA and plasma cytokine levels after a 3-h run.
David C. Nieman,J. M. Davis,Dru A. Henson,J. Walberg-Rankin,M. Shute,Charles L. Dumke,Alan C. Utter,Debra M. Vinci,James A. Carson,Adrienne S. Brown,W J. Lee,Steven R. McAnulty,Lisa S. McAnulty +12 more
TL;DR: Sixteen experienced marathoners ran on treadmills for 3 h at ∼70% maximal oxygen consumption (V˙o 2 max) on two occasions while receiving 1 l/h carbohydrate (CHO) or placebo (Pla) beverages.
Journal ArticleDOI
Interleukin-6 and cachexia in ApcMin/+ mice
Kristen A. Baltgalvis,Franklin G. Berger,Maria Marjorette O. Peña,J. Mark Davis,Stephanie J. Muga,James A. Carson +5 more
TL;DR: It is demonstrated that IL-6 is necessary for the onset of adipose and skeletal muscle wasting in the Apc(Min/+) mouse and that circulating IL- 6 can regulate Apc (Min/+)/IL-6(-/-) mouse tumor burden.
Journal ArticleDOI
The Regulation of Skeletal Muscle Protein Turnover during the Progression of Cancer Cachexia in the ApcMin/+ Mouse
James P. White,John W. Baynes,Stephen Welle,Matthew C. Kostek,Lydia E. Matesic,Shuichi Sato,James A. Carson +6 more
TL;DR: The %MPS reduction during the initiation of cachesxia is associated with IGF-1/mTOR signaling repression, while muscle AMPK activation and activation of ATP independent protein degradation occur later in the progression of cachexia.
Journal ArticleDOI
CARBOHYDRATE INGESTION INFLUENCES SKELETAL MUSCLE CYTOKINE mRNA AND PLASMA CYTOKINE LEVELS AFTER A 3-H RUN
David C. Nieman,J. M. Davis,Dru A. Henson,J. Walberg-Rankin,M. Shute,Charles L. Dumke,Alan C. Utter,Debra M. Vinci,James A. Carson,Adrienne S. Brown,W J. Lee,Steven R. McAnulty,Lisa S. McAnulty +12 more
TL;DR: CHO compared with Pla beverage ingestion attenuates the increase in plasma IL-6, IL-10, and IL-1ra and gene expression for IL-8 in athletes running 3 h at 70% Vo(2 max) despite no differences in muscle glycogen content.
Journal ArticleDOI
IL-6 regulation on skeletal muscle mitochondrial remodeling during cancer cachexia in the Apc Min/+ mouse
James P. White,Melissa J. Puppa,Shuichi Sato,Song Gao,Robert L. Price,John W. Baynes,Matthew C. Kostek,Lydia E. Matesic,James A. Carson +8 more
TL;DR: Altered expression of proteins regulating mitochondrial biogenesis and fusion are early events in the initiation of cachexia regulated by IL-6, which precede the loss of muscle mitochondrial content, and can be rescued with moderate exercise training even in the presence of high circulating IL- 6 levels.