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James E. Dalen

Researcher at University of Arizona

Publications -  300
Citations -  28906

James E. Dalen is an academic researcher from University of Arizona. The author has contributed to research in topics: Pulmonary embolism & Myocardial infarction. The author has an hindex of 73, co-authored 300 publications receiving 28280 citations. Previous affiliations of James E. Dalen include RMIT University & Baylor College of Medicine.

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A population-based perspective of the hospital incidence and case-fatality rates of deep vein thrombosis and pulmonary embolism. The Worcester DVT Study

TL;DR: Extrapolation of the data from this population-based study suggests that there are approximately 170,000 new cases of clinically recognized venous thromboembolism in patients treated in short-stay hospitals in the United States each year, and 99,000 hospitalizations for recurrent disease.
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Thrombolysis in Myocardial Infarction (TIMI) Trial, Phase I: A comparison between intravenous tissue plasminogen activator and intravenous streptokinase. Clinical findings through hospital discharge.

TL;DR: In patients with acute myocardial infarction, rt-PA elicited reperfusion in twice as many occluded infarct-related arteries as compared with SK at each of seven serial observations during the first 90 min after onset of treatment.
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Oral Anticoagulants: Mechanism of Action, Clinical Effectiveness, and Optimal Therapeutic Range

TL;DR: The mainstay treatment for atrial fibrillation is Coumadin Aspirin Reinfarction, but the use of aspirin for other reasons is also being considered.
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Heparin and Low-Molecular-Weight Heparin Mechanisms of Action, Pharmacokinetics, Dosing, Monitoring, Efficacy, and Safety

TL;DR: This chapter will review the mechanisms of action of heparin and LMWHs, their pharmacokinetics, anticoagulant effects, side effects, and laboratory monitoring, and the results of clinical trials will be discussed.
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Platelet-Active Drugs: The Relationships Among Dose, Effectiveness, and Side Effects

TL;DR: Abbreviations: ACE trial 5 Acetylsalicylic Acid and Carotid Endarterectomy; CAPRIE study 5 Clopidogrel vs Aspirin in Patients at Risk of Ischemic Events; CI 5 confidence interval; COX 5 cyclooxygenase; DVT 5 deep venous thrombosis; EPISTENT trial 5 Evaluation of Platelet IIb/IIIa Inhibitors for Stenting.