J
James F. Southern
Researcher at Medical College of Wisconsin
Publications - 125
Citations - 13386
James F. Southern is an academic researcher from Medical College of Wisconsin. The author has contributed to research in topics: Optical coherence tomography & Optical Biopsy. The author has an hindex of 46, co-authored 124 publications receiving 13097 citations. Previous affiliations of James F. Southern include Massachusetts Institute of Technology & All India Institute of Medical Sciences.
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Journal ArticleDOI
In Vivo Endoscopic Optical Biopsy with Optical Coherence Tomography
Guillermo J. Tearney,Mark E. Brezinski,Mark E. Brezinski,Brett E. Bouma,Brett E. Bouma,Stephen A. Boppart,Stephen A. Boppart,Costas Pitris,Costas Pitris,James F. Southern,James F. Southern,James G. Fujimoto,James G. Fujimoto +12 more
TL;DR: Optical coherence tomography was adapted to allow high-speed visualization of tissue in a living animal with a catheter-endoscope 1 millimeter in diameter, and was used to obtain cross-sectional images of the rabbit gastrointestinal and respiratory tracts at 10-micrometer resolution.
Journal Article
In Vivo Endoscopic Optical Biopsy with Optical Coherence Tomography
Guillermo J. Tearney,Mark E. Brezinski,Brett E. Bouma,Stephen A. Boppart,Costas Pitris,James F. Southern,James G. Fujimoto +6 more
TL;DR: In this article, optical coherence tomography was adapted to allow high-speed visualization of tissue in a living animal with a catheter-endoscope 1 millimeter in diameter, which was used to obtain cross-sectional images of the rabbit gastrointestinal and respiratory tracts at 10-micrometer resolution.
Journal ArticleDOI
Optical biopsy and imaging using optical coherence tomography.
James G. Fujimoto,Mark E. Brezinski,Guillermo J. Tearney,Stephen A. Boppart,Brett E. Bouma,Michael R. Hee,James F. Southern,Eric A. Swanson +7 more
TL;DR: Preliminary studies indicate the feasibility of developing OCT for a wide range of clinical and research diagnostic imaging applications, and the ability to non-excisionally evaluate tissue morphology using a catheter or an endoscope could have a significant impact on the diagnosis and management of a widerange of diseases.
Journal ArticleDOI
Determination of the refractive index of highly scattering human tissue by optical coherence tomography.
Guillermo J. Tearney,Mark E. Brezinski,James F. Southern,Brett E. Bouma,Michael R. Hee,James G. Fujimoto +5 more
TL;DR: Two new techniques, based on optical coherence tomography (OCT), for determining the refractive index of highly scattering human tissue are described, using OCT to track the focal length shift that results from translating the focus along the optic axis within the tissue.
Journal ArticleDOI
Magnetic resonance images lipid, fibrous, calcified, hemorrhagic, and thrombotic components of human atherosclerosis in vivo.
Jean-Franc¸ois Toussaint,Glenn M. LaMuraglia,James F. Southern,Valentin Fuster,Howard L. Kantor +4 more
TL;DR: MRI is the first noninvasive imaging technique that allows the discrimination of lipid cores, fibrous caps, calcifications, normal media, and adventitia in human atheromatous plaques in vivo.