J
James R. Bading
Researcher at City of Hope National Medical Center
Publications - 71
Citations - 6823
James R. Bading is an academic researcher from City of Hope National Medical Center. The author has contributed to research in topics: In vivo & Cancer. The author has an hindex of 35, co-authored 71 publications receiving 6380 citations. Previous affiliations of James R. Bading include Beckman Research Institute & University of Southern California.
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Journal ArticleDOI
Clearance of Alzheimer's amyloid-ss(1-40) peptide from brain by LDL receptor-related protein-1 at the blood-brain barrier.
Masayoshi Shibata,Shinya Yamada,S. Ram Kumar,Miguel Calero,James R. Bading,Blas Frangione,David M. Holtzman,Carol A. Miller,Dudley K. Strickland,Jorge Ghiso,Berislav V. Zlokovic +10 more
TL;DR: It is concluded that the BBB removes Ass from the brain largely via age-dependent, LRP-1-mediated transport that is influenced by alpha(2)M and/or apoE, and may be impaired in AD.
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Bioactivity and Safety of IL13Rα2-Redirected Chimeric Antigen Receptor CD8+ T Cells in Patients with Recurrent Glioblastoma
Christine E. Brown,Behnam Badie,Michael E. Barish,Lihong Weng,Julie R. Ostberg,Wen-Chung Chang,Araceli Naranjo,Renate Starr,Jamie Wagner,Christine Wright,Yubo Zhai,James R. Bading,Julie A. Ressler,Jana Portnow,Massimo D'Apuzzo,Stephen J. Forman,Michael C. Jensen +16 more
TL;DR: These findings provide promising first-in-human clinical experience for intracranial administration of IL13Rα2-specific CAR T cells for the treatment of GBM, establishing a foundation on which future refinements of adoptive CAR T-cell therapies can be applied.
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Imaging of Cell Proliferation: Status and Prospects
TL;DR: The most promising use for thymidine and its analogs is in monitoring tumor treatment response, as demonstrated in animal studies and pilot human trials.
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Hyperspectral and multispectral bioluminescence optical tomography for small animal imaging
Abhijit J. Chaudhari,Felix Darvas,James R. Bading,Rex Moats,Peter S. Conti,Desmond J. Smith,Simon R. Cherry,Richard M. Leahy +7 more
TL;DR: A framework for fully 3D bioluminescence tomographic image acquisition and reconstruction that exploits spectral information is described and regularized tomographic reconstruction techniques that use semi-infinite slab or FEM-based diffusion approximations of photon transport through turbid media are described.
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MicroPET and autoradiographic imaging of breast cancer alpha v-integrin expression using 18F- and 64Cu-labeled RGD peptide.
TL;DR: Overall molecular charge and characteristics of Radiolabels have profound effects on tumor accumulation and in vivo kinetics of radiolabeled RGD peptide.