Jan Fawcett

TL;DR: The magnitude of benefit of antidepressant medication compared with placebo increases with severity of depression symptoms and may be minimal or nonexistent, on average, in patients with mild or moderate symptoms.

TL;DR: The authors studied 954 psychiatric patients with major affective disorders and found that nine clinical features were associated with suicide, drawing attention to the importance of standardized prospective data for studies of suicide, assessment of short-term suicide risk factors, and anxiety symptoms as modifiable Suicide risk factors within a clinically relevant period.

TL;DR: Adding severity of anxiety and agitation to current assessments may help identify patients at acute risk and suggest effective treatment interventions and protect this group from suicide.

TL;DR: In two studies of depressed, manic, schizophrenic, and normal subjects, a scale for measuring the intensity of subjects' pleasureable responses to normally emjoyable situations (the Pleasure Scale) evidenced good internal reliability and moderate agreement with the Chapman Anhedonia Scale and Indexes of depressive symptom severity as discussed by the authors.