J
Jan W. Schoones
Researcher at Leiden University Medical Center
Publications - 140
Citations - 4384
Jan W. Schoones is an academic researcher from Leiden University Medical Center. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 32, co-authored 100 publications receiving 3340 citations. Previous affiliations of Jan W. Schoones include Loyola University Medical Center & Leiden University.
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Journal ArticleDOI
Synovial inflammation, immune cells and their cytokines in osteoarthritis: a review
B.J.E. de Lange-Brokaar,Andreea Ioan-Facsinay,G.J.V.M. van Osch,Anne-Marie Zuurmond,Jan W. Schoones,René E. M. Toes,Twj Huizinga,Margreet Kloppenburg +7 more
TL;DR: Inflammation is common in OA ST and characterized by immune cell infiltration and cytokine secretion, which seems quantitatively and qualitatively different from inflammation in RA.
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Dynamic exercise programs (aerobic capacity and/or muscle strength training) in patients with rheumatoid arthritis.
Emalie J. Hurkmans,Florus van der Giesen,Thea P. M. Vliet Vlieland,Jan W. Schoones,Els C.H.M. Van den Ende +4 more
TL;DR: Based on the evidence, aerobic capacity training combined with muscle strength training is recommended as routine practice in patients with RA and four different dynamic exercise programs were found.
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Ectopic Fat and Insulin Resistance: Pathophysiology and Effect of Diet and Lifestyle Interventions
Marieke Snel,Jacqueline T. Jonker,Jan W. Schoones,Hildo J. Lamb,A. de Roos,Hanno Pijl,Jan W. A. Smit,Arend E Meinders,Ingrid M. Jazet +8 more
TL;DR: The mechanisms of ectopic fat depositions in the liver, skeletal muscle, and in and around the heart and the consequences for each organs function are described and the effects of diet-induced weight loss and exercise on ectopicfat depositions are reviewed.
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What is the evidence for the presence of a therapeutic window of opportunity in rheumatoid arthritis? A systematic literature review
J. A. B. van Nies,A. Krabben,Jan W. Schoones,Twj Huizinga,Margreet Kloppenburg,A.H.M. van der Helm-van Mil +5 more
TL;DR: Even when heterogeneity of patients is taken into account, prolonged symptom duration is associated with radiographic progression and a lower chance on DMARD-free sustained remission and these data may support the presence of a ‘window of opportunity’.
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Risk of hypothyroidism following hemithyroidectomy: systematic review and meta-analysis of prognostic studies.
Herman Verloop,Marloes Louwerens,Jan W. Schoones,Job Kievit,Johannes W. A. Smit,Olaf M. Dekkers +5 more
TL;DR: This meta-analysis showed that approximately one in five patients will develop hypothyroidism after hemithyroidectomy, with clinical hyp Timothyroidism in one of 25 operated patients.