J
Janet Hoenicka
Researcher at University of Granada
Publications - 86
Citations - 6789
Janet Hoenicka is an academic researcher from University of Granada. The author has contributed to research in topics: Gene & ANKK1. The author has an hindex of 29, co-authored 76 publications receiving 5698 citations. Previous affiliations of Janet Hoenicka include Spanish National Research Council & Autonomous University of Madrid.
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Journal ArticleDOI
The ANKK1/DRD2 locus is a genomic substrate for affective priming and recognition of angry faces
TL;DR: It is hypothesized that emotion‐related cognitive phenomena are associated with TaqIA (rs18000497) SNP (single nucleotide polymorphism) of the ANKK1 gene and with C957T (rs6277) SNP of the DRD2 gene.
Journal ArticleDOI
Regulatory rare variants of the dopaminergic gene ANKK1 as potential risk factors for Parkinson's disease.
Estela Pérez-Santamarina,Pedro J. Garcia-Ruiz,Dolores Martínez-Rubio,Mario Ezquerra,Irene Pla-Navarro,Jorge Puente,María José Martí,Francesc Palau,Janet Hoenicka +8 more
TL;DR: The contribution of rare variants of the dopamine-related gene ANKK1 in Parkinson's disease was defined in this article, where the authors found in 10 out of 535 PD patients 6 rare variants located at the 5′UTR, the first exon, intron 1, and the nearby enhancer located 2.6kb upstream.
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Effective therapeutic strategies in a pre-clinical mouse model of Charcot-Marie-tooth disease.
Cristina Nuevo-Tapioles,Fulvio Santacatterina,Brenda Sánchez-Garrido,Cristina Núñez de Arenas,Adrián Robledo-Bérgamo,Paula Martínez-Valero,Paula Martínez-Valero,Lara Cantarero,Beatriz Pardo,Beatriz Pardo,Janet Hoenicka,Michael P. Murphy,Jorgina Satrústegui,Jorgina Satrústegui,Francesc Palau,José M. Cuezva +15 more
TL;DR: In this article, drug-repurposing approach was used to find drugs in an FDA-approved library that could prevent development of CMT disease in the Gdap1-null mouse model.
Journal ArticleDOI
Unique origin and low penetrance of the 946delGAG mutation in Valencian DYT1 families
J Carmona,Juan A. Burguera,Belén Mollá,F Mulas,Patricia Smeyers,F Carratalà,J.G. de Yébenes,Janet Hoenicka,Francesc Palau +8 more
TL;DR: This finding indicates that 18% of families may be diagnosed as DYT1 and that penetrance is reduced, and postulates a unique origin for the 946delGAG mutation in the Land of Valencia and proposes that it might have occurred at the beginning of the second millennium.
Journal ArticleDOI
Decoding Neuromuscular Disorders Using Phenotypic Clusters Obtained From Co-Occurrence Networks.
Elena Díaz-Santiago,M. Gonzalo Claros,Raquel Yahyaoui,Yolanda de Diego-Otero,Rocío Calvo,Janet Hoenicka,Francesc Palau,Juan A. G. Ranea,James R. Perkins +8 more
TL;DR: In this article, the authors presented an approach using systems biology to produce functionally coherent phenotype clusters that provide insight into the cellular functions and phenotypic patterns underlying NMDs, using the Human Phenotype Ontology as a common framework.