J
Jarmila Vinšová
Researcher at Charles University in Prague
Publications - 141
Citations - 2872
Jarmila Vinšová is an academic researcher from Charles University in Prague. The author has contributed to research in topics: Antimycobacterial & Salicylanilide. The author has an hindex of 29, co-authored 126 publications receiving 2259 citations. Previous affiliations of Jarmila Vinšová include University of Pardubice.
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Journal ArticleDOI
Recent advances in drugs and prodrugs design of chitosan.
Jarmila Vinšová,Eva Vavrikova +1 more
TL;DR: The aim of this review is to outline the recent advances in chitosan molecular modeling, especially its usage as a prodrug or drug in a field of antibacterial, anticarcinogenic and antioxidant activity.
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Synthesis and antimicrobial evaluation of new 2-substituted 5,7-di-tert-butylbenzoxazoles.
Jarmila Vinšová,Katerina Cermakova,Alexandra Tomeckova,Martina Ceckova,Josef Jampilek,Pavel Cermak,Jiri Kunes,Martin Dolezal,Frantisek Staud +8 more
TL;DR: The correlation between RP-HPLC retention parameter log K (the logarithm of capacity factor K) and various calculated log P data is shown and structure-activity relationships among the chemical structures, the physical properties and the biological activities of the evaluated compounds are discussed.
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A new modification of anti-tubercular active molecules.
Aleš Imramovský,Slovenko Polanc,Jarmila Vinšová,Marijan Kočevar,Josef Jampilek,Zuzana Reckova,Jarmila Kaustová +6 more
TL;DR: The synthesis is based on derivatives that originate from isonicotinoyl hydrazide, pyrazinamide, p-aminosalicylic acid, ethambutol, and ciprofloxacin and the lipophilicity, hydrolysis, and antituberculotic activity as well as the structure-lipophILicity and structure-activity relationships are discussed.
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Antimicrobial activity of sulfonamides containing 5-chloro-2-hydroxybenzaldehyde and 5-chloro-2-hydroxybenzoic acid scaffold.
Martin Krátký,Jarmila Vinšová,Marie Volková,Vladimír Buchta,František Trejtnar,Jiřina Stolaříková +5 more
TL;DR: A series of novel sulfonamides containing 5-chloro-2-hydroxybenzoic acid scaffolds and derivatives have shown the best activity against M. kansasii at the concentrations of 1-4 μmol/L, and the efficacy against other strains was weaker and the studied derivatives exhibited almost none antifungal potency.
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Synthesis and antimycobacterial evaluation of substituted pyrazinecarboxamides
Martin Dolezal,Pavlina Cmedlova,Lukas Palek,Jarmila Vinšová,Jiri Kunes,Vladimír Buchta,Josef Jampilek,Katarina Kralova +7 more
TL;DR: Structural-activity relationships among the chemical structures, the antimycobacterial, antifungal, photosynthesis inhibiting and antialgal activity of the evaluated substituted N-phenylpyrazine-2-carboxamides are discussed.