J
Javier Ávila-Román
Researcher at University of Seville
Publications - 31
Citations - 817
Javier Ávila-Román is an academic researcher from University of Seville. The author has contributed to research in topics: Colitis & Medicine. The author has an hindex of 12, co-authored 25 publications receiving 481 citations. Previous affiliations of Javier Ávila-Román include Rovira i Virgili University.
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Bioactive Compounds Isolated from Microalgae in Chronic Inflammation and Cancer.
Elena Talero,Sofía García-Mauriño,Javier Ávila-Román,Azahara Rodríguez-Luna,Antonio Montero Alcaide,Virginia Motilva +5 more
TL;DR: Main mechanisms of actions of these compounds in the chemoprevention of these cancers include suppression of cell proliferation, induction of apoptosis, stimulation of antimetastatic and antiangiogenic responses and increased antioxidant and anti-inflammatory activity.
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Fucoxanthin-Containing Cream Prevents Epidermal Hyperplasia and UVB-Induced Skin Erythema in Mice
Azahara Rodríguez-Luna,Javier Ávila-Román,M.L. González-Rodríguez,María José Cózar,Antonio M. Rabasco,Virginia Motilva,Elena Talero +6 more
TL;DR: FX, administered in a topical formulation, could be a novel natural adjuvant for preventing exacerbations associated with skin inflammatory pathologies as well as protecting skin against UV radiation.
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Chemoprevention with phytonutrients and microalgae products in chronic inflammation and colon cancer.
TL;DR: Mechanisms by which naturally occurring compounds may mediate chemopreventive effects on cancer include induction of cell cycle arrest and apoptosis, inhibition of cell proliferation, stimulation of antimetastatic and antiangiogenic responses and increased antioxidant and anti-inflammatory activity.
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Inhibition of chronic ulcerative colitis-associated adenocarcinoma development in mice by VSL#3.
Elena Talero,Samir Bolivar,Javier Ávila-Román,Antonio Montero Alcaide,Stefano Fiorucci,Virginia Motilva +5 more
TL;DR: Prophylactic or concurrent VSL#3 administration attenuated the disease activity index score and colon inflammation after 5, 10, and 15 cycles of DSS, as well as reduced the histological alterations and the incidence of colonic dysplastic lesions at the 3 periods studied.
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Fucoxanthin and Rosmarinic Acid Combination Has Anti-Inflammatory Effects through Regulation of NLRP3 Inflammasome in UVB-Exposed HaCaT Keratinocytes
TL;DR: It is demonstrated for the first time that the combination of FX and RA improved antioxidant and anti-inflammatory profiles in comparison to compounds assayed individually, by reducing UVB-induced apoptosis and the consequent ROS production.