Jawaid Akhtar

TL;DR: The present review article offers a detailed account of the design strategies employed for the synthesis of nitrogen-containing anticancer agents and a systematic analysis of the structure-activity relationship among the series.

TL;DR: The synthesis of benzimidazole linked oxadiazole derivatives designed as potential EGFR and erbB2 receptor inhibitors with anticancer and apoptotic activity were studied and compounds 7a and 7n showed normal architecture of myofibrils in cardiomyopathy study whereas only compound 7a showed nearly equal biochemical parameters when compared to control.

TL;DR: Quinazoline is a heterocyclic compound having biological activities as discussed by the authors, it is aromatic in nature having bicyclic structure containing benzene ring and pyrimidine ring.

TL;DR: Design strategies for the synthesis of isatin containing heterocyclic through their different approaches have been represented and structural insights and important account of structure-activity relationships and docking studies of isarin derivatives for the potent pharmacological profile are provided.

TL;DR: This review focuses on the current status of the research and contributions in the development of DYRK1A inhibitors, a potential target for prevention of neuro-degeneration and hence Alzheimer.