Development of a ghatti gum/poly (acrylic acid)/TiO2 hydrogel nanocomposite for malachite green adsorption from aqueous media: Statistical optimization using response surface methodology.

Targeted drug and gene delivery is the key for precision therapy. Lipid nanoparticles as non-viral vectors have attracted extensive attentions in treating a variety of diseases, such as cancer, immune disease, cardiac diseases and pathogen infection. They exhibit low immunogenicity and low cytotoxicity, which make them as the most-commonly used vectors. More importantly, their surfaces could be functionalized, which provide a platform to improve targeting and pharmacokinetic/pharmacodynamic properties. Although there has been great success to synthesize lipid nanoparticles, it remains as a challenge to produce active targeting lipid nanoparticles especially with definable targetability, high quality and good translation reproducibility. This review focus on the techniques to fabricate active targeting lipid nanoparticles. We start with a brief introduction of targeting lipid nanoparticles, followed by a focused discussion of various preparation approaches including one-pot assembly and post-insertion functionalization. The methods, mechanism and representative examples are introduced, together with the comparison of their advantages and restrictions. Finally, challenges facing formulation screening and clinical translation are discussed. • Active targeting lipid nanoparticle is a clinical-available platform for precision nanomedicine. • One-pot assembly strategy allows for feasible fabrication and modulation of targeting ligand density. • Post-insertion strategy makes it possible to conjugate antibodies and other fragile targeting ligands. • Challenges facing clinical translations of active targeting lipid nanoparticles exist. 

Fabrication of active targeting lipid nanoparticles: Challenges and perspectives

The penicillin derivative amoxicillin (AMX) plays an important role in the treatment of various types of infections caused by bacteria. However, excessive use of AMX may have negative health effects. Therefore, it is of utmost importance to detect and quantify the AMX in pharmaceutical drugs, biological fluids, and environmental samples with high sensitivity. Hence, this review article provides valuable and up-to-date information on nanostructured materials-based optical and electrochemical sensors for the detection of AMX in various biological and chemical samples. The role of using different nanostructured materials on the performance of important optical sensors such as colorimetric sensors, fluorescence sensors, surface-enhanced Raman scattering sensors, chemiluminescence/electroluminescence sensors, optical immunosensors, optical-fiber sensors, and several important electrochemical sensors based on different electrode types have been discussed. Moreover, nanocomposites, polymer, and MXenes-based electrochemical sensors have also been discussed, where such materials are being used to further enhance the sensitivity of these sensors. Furthermore, nanocomposite-based photo-electrochemical sensors and the market availability of biosensors including AMX have also been discussed briefly. Finally, conclusion, challenges and future perspectives of the above-mentioned sensing techniques for the AMX detection is presented.

Nanostructured Materials Based Optical and Electrochemical Detection of Amoxicillin Antibiotic.

This systematic review aimed to investigate the effect of mobile health (mHealth) interventions in the management of chemotherapy-induced side effects among cancer patients. Studies were obtained from the PubMed, Embase, Scopus and web of science databases on February 05, 2022. We followed the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines. In this review, we included randomized controlled trials [RCT] that used a mHealth interventions as a study intervention focused on patients undergoing chemotherapy. The relevant full texts were retrieved and independently screened based on the eligibility criteria. In total, 19 articles met the inclusion criteria and were included in this review. Of the 19 included studies, 15 were used mHealth interventions to control the symptoms and complications of chemotherapy. In 8 studies (42%) of them reported a significant improvement in the symptoms and complications of chemotherapy in the mHealth group compared to standard care group. Furthermore, in 5 cases of studies (26%) in the mHealth group, compared to standard care, they reported a significant improvement in patients' quality of life [QoL]. The result in this systematic review shown that mHealth interventions are comparable to or better than traditional care. In general, this technology improves the QoL, significantly contributes to patient satisfaction, and plays an important role in palliative and supportive care of cancer patients. 

Effect of Mobile Health Interventions for Side Effects Management in Patients Undergoing Chemotherapy: A Systematic Review

Semiconductor photocatalysts: A critical review highlighting the various strategies to boost the photocatalytic performances for diverse applications.

Recent advancements of biogenic iron nanoparticles in cancer theranostics

We approach a self-consistent technique to enhance the solar absorption by proper balance of trapping sites through hydrogenation. Understanding the impact of hydrogenation on oxygen vacancy sites in CeO2is crucial...

Autonomous self optimizing defects by refining energy levels through hydrogenation in CeO2-x polymorphism: A walking mobility of oxygen vacancy with enhanced adsorption capabilities and photocatalytic stability

Jay Singh

Papers

Recent advancements of biogenic iron nanoparticles in cancer theranostics

Autonomous self optimizing defects by refining energy levels through hydrogenation in CeO2-x polymorphism: A walking mobility of oxygen vacancy with enhanced adsorption capabilities and photocatalytic stability

Trends of bioderived carbonaceous materials for futuristic biomedical applications

Phase modulation kinetics in TiO2 by manipulating pH: A dynamic of photoactivity at different combination of phase and pH

Potentialities of Nanostructured SnS2 for Electrocatalytic Water Splitting: A Review