J
Jayani Pathirana
Researcher at University of London
Publications - 5
Citations - 277
Jayani Pathirana is an academic researcher from University of London. The author has contributed to research in topics: Population & Pneumonia. The author has an hindex of 3, co-authored 5 publications receiving 209 citations. Previous affiliations of Jayani Pathirana include Medical Research Council.
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Journal ArticleDOI
Effect of the introduction of pneumococcal conjugate vaccination on invasive pneumococcal disease in The Gambia: a population-based surveillance study
Grant A. Mackenzie,Grant A. Mackenzie,Philip C. Hill,David Jeffries,Ilias Hossain,Uchendu Uchendu,David Ameh,Malick Ndiaye,Oyedeji Adeyemi,Jayani Pathirana,Yekini Olatunji,Bade Abatan,Bilquees S Muhammad,Augustin E Fombah,Debasish Saha,Ian D. Plumb,Aliu Akano,Bernard E. Ebruke,Readon C. Ideh,Bankole Peter Kuti,Peter Githua,Emmanuel Olutunde,Ogochukwu Ofordile,Edward Green,Effua Usuf,Henry Badji,Usman N. Ikumapayi,Ahmad Manjang,Rasheed Salaudeen,E David Nsekpong,Sheikh Jarju,Martin Antonio,Martin Antonio,Martin Antonio,Sana Sambou,Lamin Ceesay,Yamundow Lowe-Jallow,Momodou Jasseh,Kim Mulholland,Maria Deloria Knoll,Orin S. Levine,Stephen R. C. Howie,Stephen R. C. Howie,Stephen R. C. Howie,Richard A. Adegbola,Brian Greenwood,Tumani Corrah +46 more
TL;DR: The Gambian PCV programme reduced the incidence of invasive pneumococcal disease in children aged 2–59 months by around 55% and further surveillance is needed to ascertain the maximum effect of the vaccine in the 2–4 years and older age groups, and to monitor serotype replacement.
Journal ArticleDOI
Impact of the introduction of pneumococcal conjugate vaccination on pneumonia in The Gambia: population-based surveillance and case-control studies.
Grant A. Mackenzie,Grant A. Mackenzie,Philip C. Hill,Shah M Sahito,David Jeffries,Ilias Hossain,Christian Bottomley,Uchendu Uchendu,David Ameh,Malick Ndiaye,Chidebereh D Osuorah,Oyedeji Adeyemi,Jayani Pathirana,Yekini Olatunji,Bade Abatan,Ebirim Ahameefula,Bilquees S Muhammad,Augustin E Fombah,Debasish Saha,Roslyn Mackenzie,Ian D. Plumb,Aliu Akano,Bernard E. Ebruke,Readon C. Ideh,Bankole Peter Kuti,Peter Githua,Emmanuel Olutunde,Ogochukwu Ofordile,Edward Green,Effua Usuf,Henry Badji,Usman N. Ikumapayi,Ahmad Manjang,Rasheed Salaudeen,E David Nsekpong,Sheikh Jarju,Martin Antonio,Martin Antonio,Sana Sambou,Lamin Ceesay,Yamundow Lowe-Jallow,Dawda Sowe,Momodou Jasseh,Kim Mulholland,Maria Deloria Knoll,Orin S. Levine,Stephen R. C. Howie,Stephen R. C. Howie,Stephen R. C. Howie,Richard A. Adegbola,Brian Greenwood,Tumani Corrah +51 more
TL;DR: The introduction of PCV in The Gambia was associated with a moderate impact on the incidence of radiological pneumonia, a small reduction in cases of hospitalised pneumonia, and substantial reductions of pneumococcal and hypoxic pneumonia in young children.
Journal ArticleDOI
Child Mortality after Discharge from a Health Facility following Suspected Pneumonia, Meningitis or Septicaemia in Rural Gambia: A Cohort Study.
Aakash Varun Chhibber,Philip C. Hill,James Jafali,Momodou Jasseh,Mohammad Ilias Hossain,Malick Ndiaye,Jayani Pathirana,Brian Greenwood,Grant A. Mackenzie +8 more
TL;DR: Gambian children experience increased mortality after discharge from primary and secondary care, and interventions should target both moderately and severely malnourished children.
Journal ArticleDOI
Impact of the introduction of pneumococcal conjugate vaccination on invasive pneumococcal disease and pneumonia in The Gambia: 10 years of population-based surveillance.
Grant A. Mackenzie,Philip C. Hill,David Jeffries,Malick Ndiaye,Shah M Sahito,Ilias Hossain,Uchendu Uchendu,David Ameh,Oyedeji Adeyemi,Jayani Pathirana,Yekini Olatunji,Baderinwa Abatan,Bilquees S Muhammad,Ebirim Ahameefula,Augustin E Fombah,Banjo Adeshola,Babila G Lobga,Debasish Saha,Roslyn Mackenzie,Aderonke Odutola,Ian D. Plumb,Aliu Akano,Bernard E. Ebruke,Readon C. Ideh,Bankole Kuti,Peter Githua,Emmanuel Olutunde,Ogochukwu Ofordile,Edward Green,Effua Usuf,Henry Badji,Usman Na Ikumapayi,Ahmed Manjang,Rasheed Salaudeen,E David Nsekpong,Sheikh Jarju,Martin Antonio,Martin Antonio,Sana Sambou,Lamin Ceesay,Yamundow Lowe-Jallow,Sidat Fofana,Momodou Jasseh,Kim Mulholland,Maria Deloria Knoll,Orin S. Levine,Stephen R. C. Howie,Stephen R. C. Howie,Stephen R. C. Howie,Richard A. Adegbola,Brian Greenwood,T Corrah +51 more
TL;DR: In this article, the authors compared the long-term impact of pneumococcal conjugate vaccine (PCV7) and PCV13 on IPD and radiological pneumonia in rural Gambia.
Posted ContentDOI
Aetiology of Lobar Pneumonia Determined by Multiplex Molecular Analyses of Lung and Pleural Aspirate Specimens in The Gambia
Grant A. Mackenzie,McLellan J,Machuka E,Malick Ndiaye,Jayani Pathirana,Augustin E Fombah,Baderinwa Abatan,Ilias Hossain,Aji Matty Manjang,Brian Greenwood,P.C. Hill +10 more
TL;DR: In this article, the causes of lobar pneumonia in rural Gambia using lung aspiration were determined using a multiplex PCR assay on lung and 4 pleural aspirates and the odds ratio of vaccine-type pneumococcal pneumonia in patients with two or three compared to zero doses of PCV was 0.17 (95% CI 0.06, 0.51).