J
Jayati Mullick
Researcher at National Institute of Virology
Publications - 47
Citations - 1808
Jayati Mullick is an academic researcher from National Institute of Virology. The author has contributed to research in topics: Complement system & Complement control protein. The author has an hindex of 25, co-authored 45 publications receiving 1715 citations. Previous affiliations of Jayati Mullick include University of Pennsylvania & Savitribai Phule Pune University.
Papers
More filters
Journal ArticleDOI
Targeting of NH2-terminal–processed Microsomal Protein to Mitochondria: A Novel Pathway for the Biogenesis of Hepatic Mitochondrial P450MT2
Sankar Addya,Hindupur K. Anandatheerthavarada,Gopa Biswas,Shripad V. Bhagwat,Jayati Mullick,Narayan G. Avadhani +5 more
TL;DR: It is demonstrated that P4501A1 has a chimeric NH2-terminal signal that facilitates the targeting of the protein to both the ER and mitochondria, and that the positively charged residues at positions 34 and 39 are critical for mitochondrial targeting.
Journal ArticleDOI
Dual targeting of cytochrome P4502B1 to endoplasmic reticulum and mitochondria involves a novel signal activation by cyclic AMP-dependent phosphorylation at ser128.
Hindupur K. Anandatheerthavarada,Gopa Biswas,Jayati Mullick,Naresh Babu V. Sepuri,Laszlo Otvos,Debkumar Pain,Narayan G. Avadhani +6 more
TL;DR: A novel regulatory mechanism by which cAMP modulates the targeting of a protein to two distinct organelles is described, which could drive the transport of dihydrofolate reductase (DHFR) into mitochondria.
Book ChapterDOI
Structural Organization and Transcription Regulation of Nuclear Genes Encoding the Mammalian Cytochrome c Oxidase Complex
TL;DR: A well-orchestrated regulatory control and cross talks between the nuclear and mitochondrial genomes in response to changes in the mitochondrial metabolic conditions are key factors in the overall regulation of mitochondrial biogenesis.
Journal ArticleDOI
Preferential effects of nicotine and 4-(N-methyl- N-nitrosamino)-1-(3-pyridyl)-1-butanone on mitochondrial glutathione S-transferase a4-4 induction and increased oxidative stress in the rat brain
Shripad V. Bhagwat,Camasamudram Vijayasarathy,Haider Raza,Jayati Mullick,Narayan G. Avadhani +4 more
TL;DR: Evidence is provided for the occurrence of GST A4-4 enzyme activity in mammalian mitochondria, in addition to demonstrating that both mitochondria and microsomes are intracellular targets for nicotine- and NNK-induced organ toxicity.
Journal ArticleDOI
Genetic characterization of the influenza A pandemic (H1N1) 2009 virus isolates from India.
Varsha Potdar,Mandeep S. Chadha,Santosh Jadhav,Jayati Mullick,Sarah S. Cherian,Akhilesh C. Mishra +5 more
TL;DR: The majority of the 13 Indian isolates grouped in the globally most widely circulating H1N1pdm clade 7, and a D222G mutation in the HA receptor binding domain was found in two of the eight Indian isolate obtained from fatal cases.