J
Jean Emmanuel Kahn
Publications - 3
Citations - 1127
Jean Emmanuel Kahn is an academic researcher. The author has contributed to research in topics: Hypereosinophilic syndrome & Mepolizumab. The author has an hindex of 3, co-authored 3 publications receiving 995 citations.
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Journal ArticleDOI
Treatment of patients with the hypereosinophilic syndrome with mepolizumab
Marc E. Rothenberg,Amy D. Klion,Florence Roufosse,Jean Emmanuel Kahn,Peter F. Weller,Hans-Uwe Simon,Lawrence B. Schwartz,Lanny J. Rosenwasser,Johannes Ring,Elaine F. Griffin,Ann E. Haig,Paul I.H. Frewer,Jacqueline M. Parkin,Gerald J. Gleich +13 more
TL;DR: This study shows that treatment with mepolizumab, an agent designed to target eosinophils, can result in corticosteroid-sparing for patients negative for FIP1L1-PDGFRA who have the hypereos inophilic syndrome.
Journal ArticleDOI
Hypereosinophilic syndrome: a multicenter, retrospective analysis of clinical characteristics and response to therapy.
Princess U. Ogbogu,Bruce S. Bochner,Joseph H. Butterfield,Gerald J. Gleich,Johannes Huss-Marp,Jean Emmanuel Kahn,Kristin M. Leiferman,Thomas B. Nutman,Florian Pfab,Johannes Ring,Marc E. Rothenberg,Florence Roufosse,Marie-Helene Sajous,Javed Sheikh,Dagmar Simon,Hans-Uwe Simon,Miguel Stein,Andrew J. Wardlaw,Peter F. Weller,Amy D. Klion +19 more
TL;DR: This study, the largest clinical analysis of patients with HES to date, provides useful information for clinicians but also should stimulate prospective trials to optimize treatment of HES.
Journal ArticleDOI
Long-term safety of mepolizumab for the treatment of hypereosinophilic syndromes
Florence Roufosse,Jean Emmanuel Kahn,Gerald J. Gleich,Lawrence B. Schwartz,Anish Singh,Lanny J. Rosenwasser,Judah A. Denburg,Johannes Ring,Marc E. Rothenberg,Javed Sheikh,Ann E. Haig,Stephen Mallett,Deborah N. Templeton,Hector Ortega,Amy D. Klion +14 more
TL;DR: Mepolizumab was well tolerated and effective as a long-term corticosteroid-sparing agent in PDGFRA-negative HES, and the frequency of adverse events was the primary end point.