J
Jean Jacques Le Jeune
Researcher at University of Angers
Publications - 4
Citations - 624
Jean Jacques Le Jeune is an academic researcher from University of Angers. The author has contributed to research in topics: Iron oxide & Iron oxide nanoparticles. The author has an hindex of 3, co-authored 4 publications receiving 597 citations.
Papers
More filters
Journal ArticleDOI
Synthesis of Iron Oxide Nanoparticles Used as MRI Contrast Agents: A Parametric Study☆
TL;DR: This work has determined the relative importance of parameters as well as the optimal conditions for obtaining uncoated stable particles with an average size of 5 nm and interesting relaxivities and proposed model of synthesis, related to spontaneous emulsification of suspensions, is proposed.
Journal ArticleDOI
Phosphorylcholine Coating of Iron Oxide Nanoparticles
TL;DR: In order to develop thin-walled superparamagnetic nanoparticle suspensions as a contrast agent for magnetic resonance imaging, phosphorylcholine PC was used to coat iron oxide cores of 5 nm to develop weak stable positively charged suspensions.
Journal ArticleDOI
New starch-based radiotracer for lung perfusion scintigraphy
Franck Lacoeuille,François Hindré,Benoit Denizot,Francis Bouchet,Pierre Legras,Olivier Couturier,Serge Askienazy,Jean-Pierre Benoit,Jean Jacques Le Jeune +8 more
TL;DR: Starch-based microparticles exhibit all the qualities for an effective new lung perfusion agent, with clinically significant characteristics such as a lung half-life of 3 h, a lung-to-vascular ratio of 900, and a lung -to-liver ratio of 90.
Journal ArticleDOI
Introduction of the closed cranial window technique in gerbils and verification by observation of the effects of specific drugs.
TL;DR: It is indicated that, as for rats and rabbits, both ATP-sensitive and Ca2+-dependent potassium channels are present in gerbil pial vessels and play a role in hypoxia.