J
Jean-Jacques Michels
Researcher at Institut Gustave Roussy
Publications - 37
Citations - 1854
Jean-Jacques Michels is an academic researcher from Institut Gustave Roussy. The author has contributed to research in topics: Sarcoma & Population. The author has an hindex of 18, co-authored 37 publications receiving 1681 citations.
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Journal ArticleDOI
Histologic Grade, But Not SYT-SSX Fusion Type, Is an Important Prognostic Factor in Patients With Synovial Sarcoma: A Multicenter, Retrospective Analysis
Louis Guillou,Jean Benhattar,Françoise Bonichon,Gabrielle Gallagher,Philippe Terrier,Edouard Stauffer,Nicolas de Saint Aubain Somerhausen,Jean-Jacques Michels,Gernot Jundt,Dominique Ranchère Vince,Sophia Taylor,Muriel Genevay,F. Collin,Martine Trassard,Jean-Michel Coindre +14 more
TL;DR: For patients with localized SS, histologic grade but not SYT-SSX fusion type is a strong predictor of survival.
Journal ArticleDOI
Pleomorphic liposarcoma: clinicopathologic, immunohistochemical, and follow-up analysis of 63 cases: a study from the French Federation of Cancer Centers Sarcoma Group.
Sandra Gebhard,Jean-Michel Coindre,Jean-Jacques Michels,Philippe Terrier,Gérard Bertrand,Martine Trassard,Sophia Taylor,Marie-Christine Château,Bernard Marques,V. Picot,Louis Guillou +10 more
TL;DR: Pleomorphic liposarcoma is a rare, often deep-seated and limb-based aggressive and metastasizing neoplasm of late adulthood that shows a wide range of morphologic appearances, but tumor grade and histology have no effect on patient outcome.
Journal ArticleDOI
Trends in survival for patients with metastatic soft-tissue sarcoma†
Antoine Italiano,Simone Mathoulin-Pélissier,Axel Le Cesne,Philippe Terrier,Sylvie Bonvalot,Françoise Collin,Jean-Jacques Michels,Jean-Yves Blay,Jean-Michel Coindre,Binh Bui +9 more
TL;DR: The objective of this study was to determine whether the overall survival of patients with metastatic soft tissue sarcoma (STS) has improved over the last 20 years.
Journal ArticleDOI
Detection of the synovial sarcoma translocation t(X;18) (SYT;SSX) in paraffin-embedded tissues using reverse transcriptase-polymerase chain reaction: a reliable and powerful diagnostic tool for pathologists. A molecular analysis of 221 mesenchymal tumors fixed in different fixatives.
Louis Guillou,Jean-Michel Coindre,Gabrielle Gallagher,Philippe Terrier,Sandra Gebhard,Nicolas de Saint Aubain Somerhausen,Jean-Jacques Michels,Gernot Jundt,Dominique Ranchère Vince,Françoise Collin,Martine Trassard,Viviane Le Doussal,Jean Benhattar +12 more
TL;DR: This study shows that the detection of the SS t(X;18) (SYT-SSX) in paraffin-embedded tissue is feasible with a 100% specificity and an overall 96% sensitivity, provided non-Bouin's fluid fixation is used.
Journal ArticleDOI
Effect of adjuvant chemotherapy on survival in FNCLCC grade 3 soft tissue sarcomas: a multivariate analysis of the French Sarcoma Group Database
Antoine Italiano,F. Delva,Simone Mathoulin-Pélissier,A. Le Cesne,S. Bonvalot,P. Terrier,Martine Trassard,Jean-Jacques Michels,J.-Y. Blay,J.-M. Coindre,B. Bui +10 more
TL;DR: This large cohort-based analysis with long-term follow-up indicates that patients with FNCLCC grade 3 disease may benefit from AC, and young age, non-well-differentiated liposarcoma histology, deep location, bone and/or neurovascular invasion and grade 2 or 3 were significantly associated with a higher likelihood to receive AC.