J
Jean Paul Thiery
Researcher at National University of Singapore
Publications - 421
Citations - 56508
Jean Paul Thiery is an academic researcher from National University of Singapore. The author has contributed to research in topics: Neural crest & Epithelial–mesenchymal transition. The author has an hindex of 106, co-authored 403 publications receiving 51843 citations. Previous affiliations of Jean Paul Thiery include Université Paris-Saclay & Institut Gustave Roussy.
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Xenopus cadherin-11 is expressed in different populations of migrating neural crest cells
TL;DR: The cloned Xenopus homologue of cadherin-11 and studied its spatiotemporal expression pattern during early development reinforces the idea of novel functions for type II cadherins.
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Homing of hemopoietic precursor cells to the embryonic thymus: characterization of an invasive mechanism induced by chemotactic peptides.
TL;DR: Results indicate that hemopoietic precursors respond to thymic chemotactic peptides by invasive behavior, and direct interactions between basement membrane components and fibronectin receptors appear to be required for this developmentally regulated invasion process.
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Pathways of avian neural crest cell migration in the developing gut.
TL;DR: The NC-1 and E/C8 monoclonal antibodies recognize a similar population of neural crest cells as they migrate from vagal levels of the neural tube and colonize the branchial arch region of 2- to 3-day-old chicken embryos, suggesting that a mechanism more complex than a mere interaction with fibronectin may account for migration of crest-derived cells in the gut.
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The GAS6-AXL signaling network is a mesenchymal (Mes) molecular subtype–specific therapeutic target for ovarian cancer
Jane Antony,Jane Antony,Tuan Zea Tan,Zoe Kelly,Jeffrey Low,Mahesh Choolani,Chiara Recchi,Hani Gabra,Jean Paul Thiery,Jean Paul Thiery,Ruby Yun-Ju Huang,Ruby Yun-Ju Huang +11 more
TL;DR: Kinome enrichment analysis identified AXL as a particularly abundant kinase in Mes-subtype tumor tissue and cell lines and AXL-targeted therapy may improve clinical outcome for patients with Mes- Subtype ovarian cancer.
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Expression of transfected transforming growth factor alpha induces a motile fibroblast-like phenotype with extracellular matrix-degrading potential in a rat bladder carcinoma cell line.
TL;DR: It is suggested that expression of TGF alpha in an epithelial tumor cell results in the development of a motile, fibroblast-like phenotype with matrix-degrading potential, which could result in a more aggressive tumor in vivo.