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Jean-Pierre Ballini

Researcher at École Polytechnique Fédérale de Lausanne

Publications -  52
Citations -  1352

Jean-Pierre Ballini is an academic researcher from École Polytechnique Fédérale de Lausanne. The author has contributed to research in topics: Photodynamic therapy & Verteporfin. The author has an hindex of 21, co-authored 52 publications receiving 1298 citations. Previous affiliations of Jean-Pierre Ballini include École Polytechnique.

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Improved photodynamic activity of porphyrin loaded into nanoparticles: an in vivo evaluation using chick embryos

TL;DR: The meso-tetra(p-hydroxyphenyl)porphyrin (p-THPP) encapsulated in polymeric biodegradable poly(D,L-lactide-co-glycolide) (PLGA) nanoparticles proved to enhance its photodynamic activity against mammary tumour cells when compared to free drug as mentioned in this paper.
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An optical phantom with tissue-like properties in the visible for use in PDT and fluorescence spectroscopy

TL;DR: The design and characterization of optical phantoms which have the same absorption and scattering characteristics as biological tissues in a broad spectral window (between 400 and 650 nm) are presented.
Journal Article

A new drug-screening procedure for photosensitizing agents used in photodynamic therapy for CNV.

TL;DR: Fluorescence angiography and PDT after IV injection into the CAM showed strong similarities to results obtained in clinical tests of PDT in CNV associated with AMD, suggesting this model can provide valuable information about PDT mechanisms and can be used for drug-screening purposes in development of improved sensitizers for the PDT of CNV.
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Time-resolved spectrofluorometer for clinical tissue characterization during endoscopy

TL;DR: In this paper, an optical fiber-based spectrofluorometer for time-resolved fluorescence spectroscopy of biol. tissue during clin. endoscopy is presented.
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Pharmacokinetics of Tetra (m‐hydroxyphenyl)chlorin in Human Plasma and Individualized Light Dosimetry in Photodynamic Therapy

TL;DR: Results indicate that mTHPC plasma levels measured just before PDT can be used for PDT light dosimetry, and highly significant linear correlations were found between the relative mTH PC concentrations in the mucosae of these three organs.