J
Jeffrey W. Card
Researcher at National Institutes of Health
Publications - 23
Citations - 2318
Jeffrey W. Card is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Lung & Pulmonary fibrosis. The author has an hindex of 18, co-authored 22 publications receiving 2080 citations.
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Journal ArticleDOI
It's all about sex: gender, lung development and lung disease
Michelle A. Carey,Jeffrey W. Card,James W. Voltz,Samuel J. Arbes,Dori R. Germolec,Kenneth S. Korach,Darryl C. Zeldin +6 more
TL;DR: The influence of gender and sex hormones on lung development and pathology will be discussed, with specific emphasis on pulmonary fibrosis, asthma and cancer.
Journal ArticleDOI
Pulmonary applications and toxicity of engineered nanoparticles.
TL;DR: An overview of the potential usefulness of nanoparticles and nanotechnology in respiratory research and medicine is provided and important issues and recent data pertaining to nanoparticle-related pulmonary toxicity are highlighted.
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Cytochrome P450 2J2 promotes the neoplastic phenotype of carcinoma cells and is up-regulated in human tumors.
Jian Gang Jiang,Chun Lian Chen,Jeffrey W. Card,Shilin Yang,Ji Xiong Chen,Xiang Ning Fu,Yao Gui Ning,Xiao Xiao,Darryl C. Zeldin,Dao Wen Wang +9 more
TL;DR: The results strongly suggest that CYP epoxygenase 2J2 plays a previously unknown role in promotion of the neoplastic cellular phenotype and in the pathogenesis of a variety of human cancers.
Journal ArticleDOI
Arachidonic Acid Epoxygenase Metabolites Stimulate Endothelial Cell Growth and Angiogenesis via Mitogen-Activated Protein Kinase and Phosphatidylinositol 3-Kinase/Akt Signaling Pathways
Yan Wang,Xin Wei,Xiao Xiao,Xiao Xiao,Rutai Hui,Jeffrey W. Card,Michelle A. Carey,Dao Wen Wang,Darryl C. Zeldin +8 more
TL;DR: It is concluded that AA epoxygenase metabolites can promote angiogenesis, which may provide protection to ischemic tissues and the angiogenic effects of EETs involve the MAPK and PI3-kinase/Akt signaling pathways, and to some extent, the eNOS pathway.
Journal ArticleDOI
Cytochrome p450 epoxygenase promotes human cancer metastasis.
Jiangang Jiang,Yao-Gui Ning,Chen Chen,Ding Ma,Zhen-Jun Liu,Shilin Yang,Jianfeng Zhou,Xiao Xiao,Xin Zhang,Matthew L. Edin,Jeffrey W. Card,Jianing Wang,Darryl C. Zeldin,Dao Wen Wang +13 more
TL;DR: It is reported that CYP epoxygenase overexpression or EET treatment promotes tumor metastasis independent of effects on tumor growth and inhibition of CYP2J2 or CYP102 F87V may represent a novel approach to prevent metastasis of human cancers.