Jelena Cvetkovic

TL;DR: The results imply that above ground parts of all centaury species studied, could be recommended for human usage as a rich source of natural antioxidants and also in food industry as strong antimicrobial agents for food preservation.

TL;DR: Results show that ES L1 antigen-stimulated DCs are able not only to provoke, but also to sustain anti-inflammatory and regulatory responses regardless of EAE induction, with subsequent amelioration of Eae, or even protection from the disease.

TL;DR: The results suggest that the induction of tolerogenic properties of DCs through stimulation with ES L1 could represent an innovative approach for the preparation of tolerogen DC for treatment of inflammatory and autoimmune disorders.

TL;DR: It could be concluded that the investigated excretory-secretory antigens components can largely reproduce the immunomodulatory effects of the complete excretary- secretory antIGens and therefore may be considered as molecules important for creation of the anti-inflammatory milieu achieved by the parasite.

TL;DR: Prophylactic application of Trichinella spiralis excretory–secretory muscle larvae (ES L1) products ameliorates experimental autoimmune encephalomyelitis (EAE) with the same success as infection did, however, a shift to the Th2-type response in the periphery and in the central nervous system is had a striking, new feature.