Jennifer Aceves-Ripoll

TL;DR: Results show that FGF-23 reduces contractility and enhances arrhythmogenicity through intracellular Ca2+ mishandling and blocking its actions on the heart by improving sKlotho bioavailability may enhance cardiac function and reduce arrhythmic events frequently observed in ESRD.

TL;DR: Klotho is a membrane‐bound or soluble protein, originally identified as an age‐suppressing factor and regulator of mineral metabolism, which is associated with the development of renal disease and cardiac function in the context of uraemic cardiomyopathy.

TL;DR: Patients on OL-HDF maintain higher levels of antioxidant defense, which might balance the elevated oxidative stress during dialysis, although further longitudinal studies are needed.

TL;DR: This study for the first time demonstrates a positive association between oxidative stress and the risk of first and recurrent CV events in young adults.

TL;DR: La progresion de the ERC, incluso en estadios donde la caida de the funcion renal es aun moderada, se asocia con un aumento especifico de the actividad MMP-9, lo cual podria considerarse como una potencial diana terapeutica.