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Jessica A. Karl

Researcher at Rush University Medical Center

Publications -  11
Citations -  150

Jessica A. Karl is an academic researcher from Rush University Medical Center. The author has contributed to research in topics: Deep brain stimulation & Parkinson's disease. The author has an hindex of 5, co-authored 9 publications receiving 56 citations.

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Subthalamic nucleus deep brain stimulation with a multiple independent constant current-controlled device in Parkinson's disease (INTREPID): a multicentre, double-blind, randomised, sham-controlled study.

TL;DR: This double-blind, sham-controlled, randomised controlled trial provides class I evidence of the safety and clinical efficacy of subthalamic nucleus DBS with a novel multiple independent contact current-controlled (MICC) device for the treatment of motor symptoms of Parkinson's disease.
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A Novel DBS Paradigm for Axial Features in Parkinson's Disease: A Randomized Crossover Study

TL;DR: A “dual‐frequency” programming paradigm is created to address both axial and appendicular symptoms in Parkinson's disease by applying 2 overlapping LFS programs to the DBS lead, with the overlapping area focused on the optimal cathode.
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Long-Term Satisfaction and Patient-Centered Outcomes of Deep Brain Stimulation in Parkinson’s Disease

TL;DR: This is the first study to assess long-term patient satisfaction with STN DBS, and a locally developed DBS-patient-centered outcomes questionnaire was administered to PD patients >5 years post-DBS.
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A Novel Dual-Frequency Deep Brain Stimulation Paradigm for Parkinson’s Disease

TL;DR: A substantial number of patients remained on IL–IL because of subjective improvements in gait/balance, speech, or PD symptoms, and a prospective, double-blind, crossover study with objective/quantitative outcome measures is underway.
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Severe, Symptomatic, Self-limited Unilateral DBS Lead Edema Following Bilateral Subthalamic Nucleus Implantation: Case Report and Review of the Literature.

TL;DR: It is important to recognize the benign clinical course of DBS lead edema to counsel patients and avoid unnecessary treatment such as hardware removal.