J
Jessica Bux
Publications - 1
Jessica Bux is an academic researcher. The author has contributed to research in topics: Antibody & Disease. The author has co-authored 1 publications.
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TR-FRET-Based Immunoassay to Measure Ataxin-2 as a Target Engagement Marker in Spinocerebellar Ataxia Type 2
Jessica Bux,Nesli-Ece Sen,Isa-Maria Klink,Stefan Hauser,Matthis Synofzik,Ludger Schöls,Georg Auburger,Olaf Riess,Jeannette Hübener-Schmid +8 more
TL;DR: In this paper , the amount of soluble polyQ-expanded ataxin-2 in human biofluids was measured using time-resolved fluorescence energy transfer (TR-FRET) and validated measurements in human cell lines including iPSC-derived cortical neurons.