J
Jessica R. Salas
Researcher at University of California, Los Angeles
Publications - 4
Citations - 30
Jessica R. Salas is an academic researcher from University of California, Los Angeles. The author has contributed to research in topics: Hepatocyte & Medicine. The author has an hindex of 2, co-authored 2 publications receiving 15 citations.
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Journal ArticleDOI
18F-FAC PET Selectively Images Liver-Infiltrating CD4 and CD8 T Cells in a Mouse Model of Autoimmune Hepatitis.
Jessica R. Salas,Bao Ying Chen,Alicia Wong,Donghui Cheng,John S. Van Arnam,Owen N. Witte,Peter M. Clark +6 more
TL;DR: PET imaging can be used to noninvasively visualize activated leukocytes and inflamed hepatocytes in a mouse model of autoimmune hepatitis, and provided a noninvasive biomarker of the efficacy of dexamethasone for treating the autoimmune hepatitis model.
Journal ArticleDOI
Noninvasive Imaging of Drug-Induced Liver Injury with 18F-DFA PET.
Jessica R. Salas,Bao Ying Chen,Alicia Wong,Sergio Duarte,Stephanie A.K. Angarita,Gerald S. Lipshutz,Owen N. Witte,Peter M. Clark +7 more
TL;DR: PET imaging with 18F-DFA can be used to visualize and quantify drug-induced acute liver injury and may provide information on the progression from liver injury to hepatic failure.
Journal ArticleDOI
Signaling Pathways That Drive 18F-FDG Accumulation in Cancer
Jessica R. Salas,Peter M. Clark +1 more
TL;DR: Work over the past 5 years, building on studies from years prior, has identified new proteins and signaling pathways that drive glucose consumption in cancer that could suggest new uses of 18F-FDG PET in the management of cancer.
Journal ArticleDOI
Targeting deoxycytidine kinase improves symptoms in mouse models of multiple sclerosis
Bao Ying Chen,Jessica R. Salas,Alyssa O Trias,Arely Perez Rodriguez,Jonathan Tsang,Miriam Guemes,Thuc Le,Zoran Valic,H. M. Shepard,Lawrence Steinman,David Nathanson,Johannes Czernin,Owen N. Witte,Caius G. Radu,Kenneth A Schultz,Peter M. Clark +15 more
TL;DR: The results demonstrate that targeting dCK limits symptoms in EAE mice and suggest thatdCK activity is required for MOG35-55 -specific lymphocyte activation-induced proliferation, which is relevant for multiple sclerosis.