J
Jessie Xiong
Publications - 5
Citations - 3508
Jessie Xiong is an academic researcher. The author has contributed to research in topics: TRAF2 & TRAF4. The author has an hindex of 4, co-authored 5 publications receiving 3411 citations.
Papers
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Journal ArticleDOI
The TNF receptor 1-associated protein TRADD signals cell death and NF-κB activation
TL;DR: The discovery of a novel 34 kDa protein, designated TRADD, that specifically interacts with an intracellular domain of TNFR1 known to be essential for mediating programmed cell death shows that the signaling pathways for TNF-induced cell death and NF-κB activation are distinct.
Journal ArticleDOI
TRAF6 is a signal transducer for interleukin-1
TL;DR: The identification of a new TRAF family member is reported, designated TRAF6, which indicates that TRAF proteins may function as signal transducers for distinct receptor families and that TRAf6 participates in IL-1 signalling.
Journal ArticleDOI
I-TRAF is a novel TRAF-interacting protein that regulates TRAF-mediated signal transduction
TL;DR: Overexpression of I-TRAF inhibits TRAF2-mediated NF-kappa B activation signaled by CD40 and both TNF receptors, and appears as a natural regulator of TRAF function that may act by maintaining TRAFs in a latent state.
Patent
Tumor necrosis factor receptor associated factor 6 (TRAF6)
David V. Goeddel,Jessie Xiong +1 more
TL;DR: In this article, a novel tumor necrosis factor receptor associated factor number six (TRAF6) protein, which transcriptionally activates Nuclear Factor κB, is described.
Patent
Novel protein - traf6
David V. Goeddel,Jessie Xiong +1 more
TL;DR: In this paper, a novel tumor necrosis factor receptor associated factor number six (TRAF6) polypeptide, which transcriptionally activates Nuclear Factor λB, is described.