J
Jiahao Zhang
Researcher at Wuhan University
Publications - 13
Citations - 978
Jiahao Zhang is an academic researcher from Wuhan University. The author has contributed to research in topics: Medicine & Sepsis. The author has an hindex of 3, co-authored 4 publications receiving 245 citations.
Papers
More filters
Journal ArticleDOI
Reactive Oxygen Species-Induced Lipid Peroxidation in Apoptosis, Autophagy, and Ferroptosis.
Lianjiu Su,Jiahao Zhang,Hernando Gomez,Raghavan Murugan,Xing Hong,Dongxue Xu,Fan Jiang,Zhiyong Peng,Zhiyong Peng +8 more
TL;DR: This review discussed how ROS propagate lipid peroxidation chain reactions and how the products of lipidperoxidation initiate apoptosis and autophagy in current models, and summarized lipid per oxidation in pathological conditions of critical illness.
Journal ArticleDOI
Pannexin 1 mediates ferroptosis that contributes to renal ischemia/reperfusion injury.
Lianjiu Su,Xiaofang Jiang,Cheng Yang,Jiahao Zhang,Bo Chen,Yiming Li,Shijie Yao,Qin Xie,Hernando Gomez,Raghavan Murugan,Zhiyong Peng,Zhiyong Peng +11 more
TL;DR: It is demonstrated that PANX1 deletion protects against renal IRI by regulating ferroptotic cell death and is a potential therapeutic target for the management of acute kidney injury (AKI) during the perioperative period.
Journal ArticleDOI
Mitochondria ROS and mitophagy in acute kidney injury
TL;DR: Recent advances are reviewed in the understanding of the relationship between ROS and mitophagy, the differentMitophagy pathways, the relationships between mitophile and cell death, and the relevance of these processes in the pathogenesis of AKI are reviewed.
Journal ArticleDOI
Downregulation of macrophage migration inhibitory factor attenuates NLRP3 inflammasome mediated pyroptosis in sepsis-induced AKI
Tian Li,Haibing Sun,Yiming Li,Lianjiu Su,Jun Jiang,Ye Liu,Nanhui Jiang,Rong Huang,Jiahao Zhang,Zhiyong Peng +9 more
TL;DR: In this paper , the authors investigated the mechanism of MIF promoting pyroptosis in sepsis-induced AKI and showed that up-regulation of mIF in kidney tissue of mice with CLP (cecum ligation puncture) surgery and in LPS-injured human kidney-2 (HK-2) cells.
Journal ArticleDOI
Downregulation of macrophage migration inhibitory factor attenuates NLRP3 inflammasome mediated pyroptosis in sepsis-induced AKI
Tianlong Li,Haibing Sun,Yiming Li,Lianjiu Su,Jun Jiang,Ye Liu,Nanhui Jiang,Rong Huang,Jiahao Zhang,Zhiyong Peng +9 more
TL;DR: In this article , the authors investigated the mechanism of MIF promoting pyroptosis in sepsis-induced AKI and showed that up-regulation of mIF in kidney tissue of mice with CLP (cecum ligation puncture) surgery and in LPS-injured human kidney-2 (HK-2) cells.