Raghavan Murugan

TL;DR: This review discussed how ROS propagate lipid peroxidation chain reactions and how the products of lipidperoxidation initiate apoptosis and autophagy in current models, and summarized lipid per oxidation in pathological conditions of critical illness.

TL;DR: Angiotensin II effectively increased blood pressure in patients with vasodilatory shock that did not respond to high doses of conventional vasopressors.

TL;DR: It is concluded that short- and long-term risk of death or RRT is greatest when patients meet both the serum creatinine level and urine output criteria for AKI and when these abnormalities persist.

TL;DR: Emerging evidence suggests that survivors of AKI incur long-term risks for developing chronic kidney disease and end-stage renal disease compared with those without AKI, and further work is required to better understand the pathogenesis ofAKI during critical illness and to develop novel treatments.

TL;DR: In general, patients with acute kidney injury were older, had more comorbidity, and had higher biomarker concentrations (interleukin-6, tumor necrosis factor, D-dimer) even among patients without severe sepsis, which indicates acute kidneys injury is common evenamong patients with non-severe pneumonia and is associated with higher immune response and an increased risk of death.