J
Jian Li
Researcher at Hubei University of Medicine
Publications - 54
Citations - 1903
Jian Li is an academic researcher from Hubei University of Medicine. The author has contributed to research in topics: Plasmodium falciparum & Plasmodium vivax. The author has an hindex of 16, co-authored 50 publications receiving 1135 citations. Previous affiliations of Jian Li include Kangwon National University.
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Journal ArticleDOI
Immune cells within the tumor microenvironment: Biological functions and roles in cancer immunotherapy.
TL;DR: The biological functions of immune cells within TME and their roles in cancer immunotherapy are reviewed, and the perspectives of the basic studies for improving the effectiveness of the clinical use are discussed.
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Composition and divergence of coronavirus spike proteins and host ACE2 receptors predict potential intermediate hosts of SARS-CoV-2.
Zhixin Liu,Zhixin Liu,Xiao Xiao,Xiuli Wei,Jian Li,Jing Yang,Huabing Tan,Jianyong Zhu,Qiwei Zhang,Qiwei Zhang,Jianguo Wu,Jianguo Wu,Long Liu +12 more
TL;DR: Systematic comparison and analysis used to predict the interaction between the receptor‐binding domain (RBD) of coronavirus spike protein and the host receptor, angiotensin‐converting enzyme 2 (ACE2) indicated that turtles may act as the potential intermediate hosts transmitting SARS‐CoV‐2 to humans.
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Arctigenin inhibits STAT3 and exhibits anticancer potential in human triple-negative breast cancer therapy
Tingting Feng,Wei Cao,Wanxiang Shen,Liang Zhang,Xinsheng Gu,Yang Guo,Hsiang-I Tsai,Xuewen Liu,Jian Li,Jingxuan Zhang,Shan Li,Fuyun Wu,Ying Liu +12 more
TL;DR: It is demonstrated that Atn decreased proliferation, and induced apoptosis in TNBC cells, rendering Atn as a promising candidate drug for further development and for designing new effective STAT3 inhibitors.
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Profiling the humoral immune responses to Plasmodium vivax infection and identification of candidate immunogenic rhoptry-associated membrane antigen (RAMA).
Feng Lu,Jian Li,Bo Wang,Yang Cheng,Deok Hoon Kong,Liwang Cui,Kwon-Soo Ha,Jetsumon Sattabongkot,Takafumi Tsuboi,Eun-Taek Han +9 more
TL;DR: High-throughput screening assays have been applied to investigate blood stage-specific immune proteomes from P. vivax and one of the top immunogenic proteins, RAMA, was characterized and confirmed to be a serological marker of recent exposure to P.vivax infection.
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The Plasmodium vivax merozoite surface protein 1 paralog is a novel erythrocyte-binding ligand of P. vivax.
Yang Cheng,Yue Wang,Daisuke Ito,Deok-Hoon Kong,Kwon-Soo Ha,Jun-Hu Chen,Feng Lu,Jian Li,Bo Wang,Eizo Takashima,Jetsumon Sattabongkot,Takafumi Tsuboi,Eun-Taek Han +12 more
TL;DR: An in vitro cytoadherence assay showed that PvMSP1P, especially the 19-kDa C-terminal region, could bind to erythrocytes and provide further evidence that the PvM SP1P might be an essential parasite adhesion molecule in the P. vivax infection.