Showing papers by "Jianyu Li published in 2020"
TL;DR: In this article, a novel artificial ionic skin (AIskin) based on controlled ion mobility is proposed for wearable strain-humidity sensing, human-machine interaction and walking energy harvesting, which consists of a bilayer of oppositely-charged, double-network hydrogel, and converts mechanical stimuli and humidity into signals of resistance, capacitance, open-circuit voltage (OCV), and shortcircuit current.
Abstract: Skin serves as a physical and hygroscopic barrier to protect the inner body, and also contains sensory receptors to perceive environmental and mechanical stimuli. To recapitulate these salient features, hydrogel-based artificial skins have been developed. However, existing designs are constrained by limited functionality, low stability, and requirement of external power. Herein, a novel artificial ionic skin (AIskin) – an analog of the diode based on controlled ion mobility – is demonstrated with high toughness, stretchability, ambient stability and transparency. The AIskin consists of a bilayer of oppositely-charged, double-network hydrogel, and converts mechanical stimuli and humidity into signals of resistance, capacitance, open-circuit voltage (OCV), and short-circuit current (SCC), among which the OCV- and SCC-based sensing signals are self-generated. Its multimodal sensation is maintained in a wide range of relative humidities (13–85%). It is demonstrated for wearable strain-humidity sensing, human–machine interaction and walking energy harvesting. This work will open new avenues toward next-generation, skin-inspired wearable electronics.
85 citations
TL;DR: A new method called triggered micropore-forming bioprinting that can yield cell-laden scaffolds of defined architecture and interconnected pores over a range of sizes, encompassing that of many cell types, and exhibits superior mechanical robustness despite high porosity.
Abstract: Cell-laden scaffolds of architecture and mechanics that mimic those of the host tissues are important for a wide range of biomedical applications but remain challenging to bioprint. To address these challenges, we report a new method called triggered micropore-forming bioprinting. The approach can yield cell-laden scaffolds of defined architecture and interconnected pores over a range of sizes, encompassing that of many cell types. The viscoelasticity of the bioprinted scaffold can match that of biological tissues and be tuned independently of porosity and stiffness. The bioprinted scaffold also exhibits superior mechanical robustness despite high porosity. The bioprinting method and the resulting scaffolds support cell spreading, migration, and proliferation. The potential of the 3D bioprinting system is demonstrated for vocal fold tissue engineering and as an in vitro cancer model. Other possible applications are foreseen for tissue repair, regenerative medicine, organ-on-chip, drug screening, organ transplantation, and disease modeling.
45 citations
TL;DR: In this paper, the authors studied the interfacial fatigue fracture of a tissue adhesive hydrogel based on tough hydrogels, called tough adhesive (TA), using a fracture mechanics approach.
23 citations
TL;DR: This framework can offer clinicians, learners, and researchers the ability to carry out operative rehearsal, teaching, or studies involving brain tumor surgery in a controlled laboratory environment and represents a crucial step in the understanding and training of expertise in neurosurgery.
7 citations
Posted Content•
TL;DR: In this paper, a scaling analysis and computational study reveal that it stems from the scaling of shear modulus, which is a measure of the strength of a hydrogel.
Abstract: Tough adhesive hydrogels find broad applications in engineering and medicine. Such hydrogels feature high resistance against both cohesion and adhesion failure. The superior fracture properties may, however, deteriorate when the hydrogels swell upon exposure of water. The underlying correlation between the polymer fraction and fracture properties of tough adhesive hydrogels remains largely unexplored. Here we study how the cohesion and adhesion energies of a tough adhesive hydrogel evolve with the swelling process. The results reveal a similar scaling law of the two quantities on the polymer fraction. Our scaling analysis and computational study reveal that it stems from the scaling of shear modulus. The study will promote the investigation of scaling of hydrogel fracture and provide development guidelines for new tough adhesive hydrogels.