J
Jiayou Chu
Researcher at Peking Union Medical College
Publications - 73
Citations - 19374
Jiayou Chu is an academic researcher from Peking Union Medical College. The author has contributed to research in topics: Population & Haplotype. The author has an hindex of 20, co-authored 68 publications receiving 14039 citations.
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The Adaptive Change of HLA-DRB1 Allele Frequencies Caused by Natural Selection in a Mongolian Population That Migrated to the South of China.
TL;DR: It is proposed that the dramatically change of HLA frequencies in southern Mongolian was caused by a combination of inter-population gene flow and natural selection, and certain diseases specific to the south of China, such as malaria, may be the driving force behind the enhanced DRB1*12:02:01 frequency.
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Association study of telomere length with idiopathic male infertility
Shuyuan Liu,Chang-Jun Zhang,Hai-Ying Peng,Xiaoqin Huang,Hao Sun,Keqin Lin,Kai Huang,Jiayou Chu,Zhaoqing Yang +8 more
TL;DR: The results suggest that sperm telomere length is associated with idiopathic male infertility of China and the possibility that shorter telomeres in sperm chromosome will reduce spermatogenesis and sperm functions, which finally affected the fertility of male.
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CAG-repeat variant in the polymerase γ gene and male infertility in the Chinese population: a meta-analysis.
Shuyuan Liu,Chang-Jun Zhang,Hai-Ying Peng,Yufeng Yao,Lei Shi,Jin-Bao Chen,Keqin Lin,Liang Yu,Li Shi,Xiaoqin Huang,Hao Sun,Jiayou Chu +11 more
TL;DR: There is no significant difference of the frequencies of the POLG-CAG-repeat variants among six Chinese Han populations, and this polymorphism may not be associated with Chinese male infertility.
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Genetic and clinical analysis in a Chinese parkinsonism-predominant spinocerebellar ataxia type 2 family.
Hao Sun,Wataru Satake,Chang-Jun Zhang,Yoshitaka Nagai,You-Yong Tian,Shouzhi Fu,Jian-kun Yu,Ya-Ping Qian,Yuan Qian,Jiayou Chu,Tatsushi Toda +10 more
TL;DR: A large Chinese family showing primarily parkinsonism symptoms with autosomal dominant inheritance is discovered, and it is possible that variations in one or more modifier genes might account for the parkinsonist-predominant SCA2 predisposition observed in this pedigree.
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Polymorphic Alu insertions and their associations with MHC class I alleles and haplotypes in Han and Jinuo populations in Yunnan Province, southwest of China
Yufeng Yao,Li Shi,Lei Shi,Keqin Lin,Yufen Tao,Liang Yu,Hao Sun,Xiaoqin Huang,Yan-han Li,Jiayou Chu +9 more
TL;DR: The results suggest that MHC class I region haplotypes of the two studied populations might derive from different progenitor haplotypes and MHC I-POALINs are informative genetic markers for investigating origins and evolution of MHCclass I region Haplotypes in different populations.