J
Jie Gong
Researcher at Huazhong University of Science and Technology
Publications - 12
Citations - 336
Jie Gong is an academic researcher from Huazhong University of Science and Technology. The author has contributed to research in topics: Lung injury & Bronchoalveolar lavage. The author has an hindex of 8, co-authored 11 publications receiving 258 citations.
Papers
More filters
Journal ArticleDOI
Maresin 1 mitigates LPS-induced acute lung injury in mice
Jie Gong,Zhou-Yang Wu,Hong Qi,Lin Chen,Hongbin Li,Bo Li,Chengye Yao,Yaxin Wang,Jing Wu,Shiying Yuan,Shanglong Yao,You Shang +11 more
TL;DR: A LPS‐induced ALI model was used to determine whether MaR1 can mitigate lung injury and, if so, whether this can be regulated by Maresin 1.
Journal ArticleDOI
Maresin 1 prevents lipopolysaccharide-induced neutrophil survival and accelerates resolution of acute lung injury.
Jie Gong,Hong Liu,Jing Wu,Hong Qi,Zhou-Yang Wu,Huaqing Shu,Hongbin Li,Lin Chen,Yaxin Wang,Bo Li,Min Tang,Yu-dong Ji,Shiying Yuan,Shanglong Yao,You Shang +14 more
TL;DR: MaR1 promotes the resolution of L PS-induced ALI by overcoming LPS-mediated suppression of neutrophil apoptosis by overcoming the proapoptotic action of MaR1.
Journal ArticleDOI
Maresin 1 Inhibits Epithelial-to-Mesenchymal Transition in Vitro and Attenuates Bleomycin Induced Lung Fibrosis in Vivo.
Yaxin Wang,Ruidong Li,Lin Chen,Wen Tan,Zhipeng Sun,Haifa Xia,Bo Li,Yuan Yu,Jie Gong,Min Tang,Yu-dong Ji,Shiying Yuan,Shanglong Yao,You Shang +13 more
TL;DR: Data indicate that MaR1 inhibits TGF-&bgr;1-induced EMT and attenuates bleomycin-induced pulmonary fibrosis and may be a promising strategy for alleviation of lung fibrosis.
Journal ArticleDOI
BML-111, a lipoxin receptor agonist, protects haemorrhagic shock-induced acute lung injury in rats
TL;DR: BML-111 significantly mitigated acute lung injury induced by haemorrhagic shock, however, BOC-2, an antagonist of the lipoxinA(4)-receptor, partially reversed the protective effect of B ML-111.
Journal ArticleDOI
BML-111 attenuates hemorrhagic shock-induced acute lung injury through inhibiting activation of mitogen-activated protein kinase pathway in rats.
Hongbin Li,Guangzhi Wang,Jie Gong,Zhou-Yang Wu,Si Guo,Bo Li,Mei Liu,Yu-dong Ji,Min Tang,Shi-ying Yuan,You Shang,Shanglong Yao +11 more
TL;DR: This study indicates that BML-111 attenuated hemorrhagic shock-induced ALI via the MAPK/activator protein-1 signaling pathway, and may have therapeutic potential for hemorrhagicshock- induced ALI.