J
Jie Zhou
Researcher at Beijing Normal University
Publications - 1
Citations - 17
Jie Zhou is an academic researcher from Beijing Normal University. The author has contributed to research in topics: Transforming growth factor & Phosphorylation. The author has an hindex of 1, co-authored 1 publications receiving 11 citations.
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Hypoxia induces calpain activity and degrades SMAD2 to attenuate TGFβ signaling in macrophages.
TL;DR: Hypoxia interferes with TGFβ signaling in macrophages by calpain-mediated proteolysis of the central signaling component SMAD2, substantiating the ability of calpain to degradeSMAD2.