J
Jim Swoger
Researcher at European Bioinformatics Institute
Publications - 54
Citations - 4381
Jim Swoger is an academic researcher from European Bioinformatics Institute. The author has contributed to research in topics: Microscope & Light sheet fluorescence microscopy. The author has an hindex of 22, co-authored 52 publications receiving 3883 citations. Previous affiliations of Jim Swoger include Pompeu Fabra University & Max Planck Society.
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Optical sectioning deep inside live embryos by selective plane illumination microscopy
TL;DR: In this article, a selective plane illumination microscopy (SPIM) was developed to generate multidimensional images of samples up to a few millimeters in size, which can be applied to visualize the embryogenesis of the relatively opaque Drosophila melanogaster in vivo.
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High-resolution three-dimensional imaging of large specimens with light sheet–based microscopy
Peter J. Verveer,Jim Swoger,Francesco Pampaloni,Klaus Greger,Marco Marcello,Ernst H. K. Stelzer +5 more
TL;DR: It is reported that single (or selective) plane illumination microscopy (SPIM), combined with a new deconvolution algorithm, provides a three-dimensional spatial resolution exceeding that of confocal fluorescence microscopy in large samples.
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Multi-view image fusion improves resolution in three-dimensional microscopy
TL;DR: A non-blind, shift-invariant image processing technique that fuses multi-view three-dimensional image data sets into a single, high quality three- dimensional image is presented, effective for improving the resolution and isotropy in images of transparent specimens, and improving the uniformity of the image quality of partially opaque samples.
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The role of spatially controlled cell proliferation in limb bud morphogenesis.
Bernd Boehm,Henrik Westerberg,Gaja Lesnicar-Pucko,Sahdia Raja,Michael Rautschka,James Cotterell,Jim Swoger,James Sharpe +7 more
TL;DR: Oriented cell behaviors likely have a more important role in limb bud elongation during development than previously suggested by the “growth-based morphogenesis” hypothesis.
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Basic building units and properties of a fluorescence single plane illumination microscope.
TL;DR: The basic principles underlying EMBL's SPIM and its unique properties such as the efficient usage of the fluorophores, the reduced photo toxic effects, the true optical sectioning capability, and the excellent axial resolution are described.